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Topotecan
go.drugbank.com/drugs/DB01030ApprovedInvestigationalAn antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Categories: MATE 1 Substrates with a Narrow Therapeutic Index, MATE 2 Substrates with a Narrow Therapeutic IndexProducts: TEKAN-L 4 MG IV ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, Topotecan Hikma 1 mg Pulver für ein Konzentrat zur Herstellung einer InfusionslösungAmisulpride
go.drugbank.com/drugs/DB06288ApprovedInvestigationalAmisulpride is a benzamide derivative and a dopamine receptor antagonist that selectively works on dopamine D2 and D3 receptors. … a different drug class.
Synonyms: 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-O-anisamide, 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamideCategories: Dopamine D2 Receptor AntagonistsDopamine
go.drugbank.com/drugs/DB00988ApprovedInvestigationalDopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action. … One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine.
Mixtures: INYECCION DE CLORHIDRATO DE DOPAMINA EN DEXTROSA AL 5% USP (1600 MCG/ML), INYECCION DE CLORHIDRATO DE DOPAMINA 800 MCG/ML DEXTROSA AL 5% UPSCategories: Compounds used in a research, industrial, or household setting, Monoamine Oxidase A SubstratesCalcium acetate
go.drugbank.com/drugs/DB00258ApprovedThe chemical compound calcium acetate is the calcium salt of acetic acid. It has been commonly referred to as the acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form.
Mixtures: ACETATO DE ALUMINIO, ACETATO DE ALUMINIO POLVOCategories: Compounds used in a research, industrial, or household settingLosartan
go.drugbank.com/drugs/DB00678ApprovedInvestigational[L7423] Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. … [L7423] Losartan was granted FDA approval on 14 April 1995.[L7423]
Mixtures: TOZAAR PLUS LS 50/12.5mg Tablet, LOSARTAN E IDROCLOROTIAZIDE DOC GENERICICategories: Agents Acting on the Renin-Angiotensin SystemFlumazenil
go.drugbank.com/drugs/DB01205ApprovedInvestigationalFumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine … receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system.
Categories: Compounds used in a research, industrial, or household settingProducts: ANEXATE 1 MG/10 ML IV ENJ. ICIN COZ. ICEREN AMPUL, 5 ADET, ANEXATE 0,5 MG/5 ML IV ENJ. ICIN COZ. ICEREN AMPUL, 5 ADETEverolimus
go.drugbank.com/drugs/DB01590ApprovedInvestigationalIn a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and not on the mTORC2 protein. … Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: EVEROLIMUS EG, EVEROLIMUS DR. REDDY'SEletriptan
go.drugbank.com/drugs/DB00216ApprovedInvestigationalEletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine headaches.
Products: ELETRIPTAN EG, ELETRIPTAN DOC GENERICIMethadone
go.drugbank.com/drugs/DB00333ApprovedInvestigationalMethadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. … (due to a lack of active metabolites), minimal accumulation in renal failure, good bioavailability, low cost, and a long duration of action.
Categories: Drugs Used in Opioid Dependence, Drugs Used in Addictive DisordersSynonyms: dl-MethadoneFentanyl
go.drugbank.com/drugs/DB00813ApprovedIllicitInvestigationalVet approvedFentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. … Fentanyl's high potency has also made it a common adulterant in illicit drugs, especially heroin.
Synonyms: N-phenethyl-4-(N-propionylanilino)piperidine, N-(1-phenethyl-4-piperidinyl)-N-phenylpropionamideProducts: CITRATO DE FENTANILO 0.05MG/ML, Actiq 200 Mikrogramm Lutschtablette, gepresst, mit integriertem Applikator zur Anwendung in der Mundhöhle