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Choline alfoscerate
go.drugbank.com/drugs/DB04660InvestigationalA component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids. … (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules. [PubChem]
Synonyms: L-alpha-Glycerophosphocholine, L-alpha-GlycerophosphorylcholineProducts: MEDOTİLİN 1000 MG/ 4 ML IM/IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPÜL, 3 ADETAlteplase
go.drugbank.com/drugs/DB00009ApprovedInvestigationalAlteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent.[L43125] It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. … [A252330,L43125] Alteplase is a purified glycoprotein of 527 amino acids expressed in Chinese hamster ovary (CHO) cells.
Mixtures: Activase RT-PA, Lysatec RT - PaSynonyms: t-PA, rt-PADiphenhydramine
go.drugbank.com/drugs/DB01075ApprovedInvestigationalDiphenhydramine has also been shown to be implicated in a number of neurotransmitter systems that affect behaviour including dopamine, norepinephrine, serotonin, acetylcholine, and opioid [A1539]. … As a result, diphenhydramine is being investigated for its anxiolytic and anti-depressant properties.
Mixtures: VICKS FLU GIORNO NOTTE, ACTIGRIP GIORNO & NOTTESynonyms: N-(2-(diphenylmethoxy)ethyl)-N,N-dimethylamine, 2-(benzhydryloxy)-N,N-dimethylethylamineTapentadol
go.drugbank.com/drugs/DB06204ApprovedInvestigationalTapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake. … [L47291] Used in the management of pain, tapentadol is typically reserved for patients who have limited alternative treatment options.
Products: Nucynta Ir, Nucynta IR Tablets 50 mgBuserelin
go.drugbank.com/drugs/DB06719ApprovedInvestigationalIt is used in prostate cancer treatment. … Buserelin is a synthetic peptide analog of the luteinizing hormone-releasing hormone (LHRH) agonist, which stimulates the pituitary gland's gonadotrophin-releasing hormone receptor (GnRHR).
Products: Suprefact Inj 1mg/mlNavtemadlin
go.drugbank.com/drugs/DB15299InvestigationalNavtemadlin (AMG-232) is under investigation in clinical trial NCT03041688 (MDM2 Inhibitor AMG-232 and Decitabine in Treating Patients With Relapsed, Refractory, or Newly-Diagnosed Acute Myeloid Leukemia
Synonyms: {(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-1-[ (2S)-3 -methyl-1-(propan-2- ylsulfonyl)butan-2-yl]-2-oxopiperidin-3-yl}acetic acidRecurrent Chronic Lymphocytic Leukemia
go.drugbank.com/conditions/DBCOND0029141Drugs: OfatumumabSynonyms: Chronic lymphoid leukemia in relapse, Chronic lymphoid leukemia in relapse (disorder)Prednisolone
go.drugbank.com/drugs/DB00860ApprovedInvestigationalVet approvedPrednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. … [A187463] Prednisolone was granted FDA approval on 21 June 1955.[L9431]
Categories: Corticosteroids, Weak (Group I)Synonyms: Predniso(lo)neEsomeprazole
go.drugbank.com/drugs/DB00736ApprovedInvestigational[A177571] Rapid discontinuation of PPIs such as esomeprazole may cause a rebound effect and a short term increase in hypersecretion. … [A177577, A177580] Due to their good safety profile and as several PPIs are available over the counter without a prescription, their current use in North America is widespread.
Products: ESOMEN-L 40 MG IV INFUZYON/ENJEKSIYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, ESOMEN-L 20 MG IV İNFÜZYON/ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADETMannitol
go.drugbank.com/drugs/DB00742ApprovedInvestigationalMannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. … On October 30, 2020, mannitol was approved by the FDA as add-on maintenance therapy for the control of pulmonary symptoms associated with cystic fibrosis in adult patients and is currently marketed for
Mixtures: ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic), ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic)Categories: Compounds used in a research, industrial, or household setting