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Displaying results 761 - 770 of 10000 in total
  1. Drug

    NKX101

    go.drugbank.com/drugs/DB18131
    Investigational

    NKX101 is an investigational allogeneic chimeric antigen receptor (CAR)-natural killer cell therapy.

    Synonyms: a fourth generation activating chimeric receptor (ACR) natural killer (NK) cell therapy engineered with an NKG2D ACR, OX40 costimulatory domain, CD3zeta signaling moiety, and membrane bound IL-15 (mb-IL15
  2. Drug

    Lamivudine

    go.drugbank.com/drugs/DB00709
    ApprovedInvestigational

    A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. … It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).

    Mixtures: ABACAVIR 600 MG Y LAMIVUDINA 300 MG, N/ACategories: P-glycoprotein substrates, Heterocyclic Compounds, 1-Ring
  3. Drug

    Fluconazole

    go.drugbank.com/drugs/DB00196
    ApprovedInvestigational

    Fluconazole, commonly known as _Diflucan_, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. … It was initially approved by the FDA in 1990. This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole].

    Mixtures: GOTLAND CANDILOX 500/ 37.5 MG TABLETAS CUBIERTAS, FLUCONAZOL+SECNIDAZOL 75MG/1000 MGCategories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A Inhibitors
  4. Drug

    Anvatabart opadotin

    go.drugbank.com/drugs/DB18290
    Investigational

    Synonyms: ; conjugated at two engineered sites via a stable, gamma1 heavy chain humanized (1-449) [VH humanized (Homo sapiens IGHV3-66*01 (81.6%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*01, G1m17,1 (CH1 A1.4>
  5. Drug

    INVAC-1

    go.drugbank.com/drugs/DB16196
    Investigational

    INVAC-1 is under investigation in clinical trial NCT03265717 (DNA Plasmid Encoding a Modified Human Telomerase Reverse Transcriptase (Htert), Invac-1 in Chronic Lymphocytic Leukemia).

    Synonyms: Invac-1, a double stranded dna plasmid vaccine construct encoding ubiquitin-human telomerase reverse transcriptase (htert) fusion protein, Human telomerase reverse transcriptase (htert) dna vaccine invac-1
  6. Drug

    Cytarabine

    go.drugbank.com/drugs/DB00987
    ApprovedInvestigational

    A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. … Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle.

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone, 1-beta-D-Arabinofuranosylcytosine
  7. Drug

    Iomeprol

    go.drugbank.com/drugs/DB11705
    ApprovedInvestigational

    Iomeprol is a tri-iodinated, non-ionic radiographic contrast agent for intraarterial or intravenous use. … [A265090,A265095] Iomeprol first appeared in the market in 1994 [A265095] and is currently used in various diagnostic processes involving x-ray imaging and computed tomography (CT) scans.[L52260]

    Synonyms: N,N'-BIS(2,3-DIHYDROXYPROPYL)-2,4,6-TRIIODO-5-(N-METHYLGLYCOLAMIDO)ISOPHTHALAMIDE, 1,3-BENZENEDICARBOXAMIDE, N,N'-BIS(2,3-DIHYDROXYPROPYL)-5-((HYDROXYACETYL)METHYLAMINO)-2,4,6-TRIIODO-Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast Media, Iodinated
  8. Drug

    Zelpultide alfa

    go.drugbank.com/drugs/DB18587
    Investigational

    Zelpultide alfa is a recombinant human surfactant protein D.

    Synonyms: PULMONARY SURFACTANT-ASSOCIATED PROTEIN D (HUMAN RECOMBINANT GLYCOEXPRESS MYELOMA CELL HOMOTRIMERIC QUADRAPLEX AT-100), HUMAN PULMONARY SURFACTANT-ASSOCIATED PROTEIN D (PSPD, SURFACTANT PROTEIN D, SP-D, COLLECTIN-7, SURFACTANT PROTEIN D), NON-COVALENT QUADRUPLE TRIMER, PRODUCED IN HUMAN MYELOGENOUS LEUKEMIA K562 CELLS,
  9. Drug

    Albumin human

    go.drugbank.com/drugs/DB00062
    ApprovedInvestigational

    This is a biosimilar drug to existing human serum albumin and was approved for a biological license at both 5% and 25% concentrations by the FDA on June 21, 2018 [L3101]. … Each domain comprises two separate sub-domains (A and B) [A40060].

    Products: ALBUMAN 200 MG/ML 100 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET, VIALEBEX 200 MG/ML 100 ML IV İNFUZYONLUK ÇÖZELTİ
  10. Drug

    Valproic acid

    go.drugbank.com/drugs/DB00313
    ApprovedInvestigational

    [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. … a similar degree of anticonvulsive activity.

    Mixtures: EPILIM CHRONO TABLET 200 mg, EPILIM CHRONO TABLET 200 mgCategories: Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index