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Bacteroides thetaiotaomicron
go.drugbank.com/drugs/DB17879InvestigationalBacteroides thetaiotaomicron is a live biotherapeutic. … Developed by 4D Pharma, Thetanix, an oral formulation comprising lyophilized Bacteroides thetaiotaomicron, is being investigated for the treatment of Crohn’s disease.[A259892]
BEA-17
go.drugbank.com/drugs/DB18574ExperimentalBEA-17 is a small molecule targeted degrader of the epigenetic enzyme LSD1 and its co-factor CoREST.[L48330] It is under investigation for the treatment of glioblastoma.
CYNK-101
go.drugbank.com/drugs/DB18637InvestigationalCYNK-101 is an allogeneic human placental hematopoietic stem cell-derived natural killer (NK) cell therapy product that is genetically modified to express a variant of CD16 (CD16VP).
Synonyms: allogeneic human placental hematopoietic stem cell derived natural killer (NK) cell therapy product that is genetically modified to express a variant of CD16 (CD16VP)Zandatrigine
go.drugbank.com/drugs/DB19051InvestigationalZandatrigine is under investigation in clinical trial NCT05226780 (Extension Study to Evaluate How Safe and Tolerable NBI-921352 Is as an Adjunctive Therapy for Participants With SCN8A-DEE).
Synonyms: Benzenesulfonamide, 2-fluoro-5-methyl-4-(methyl((3s)-1-(phenylmethyl)-3-pyrrolidinyl)amino)-n-4-thiazolyl-Otamixaban
go.drugbank.com/drugs/DB06635InvestigationalOtamixaban is a novel direct Factor Xa (FXa) inhibitor. It is currently being developed by the French pharmaceutical company Sanofi-Aventis as a treatment for acute coronary syndrome.
Categories: Heterocyclic Compounds, 1-RingEpitestosterone
go.drugbank.com/drugs/DB07768ExperimentalEpitestosterone is the 17-alpha isomer of testosterone, derived from pregnenolone via the delta5-steroid pathway, and via 5-androstene-3-beta,17-alpha-diol. … The ratio between testosterone/epitestosterone is used to monitor anabolic drug abuse.
Synonyms: 17-alpha-Hydroxyandrost-4-en-3-one, (17-alpha)-17-Hydroxyandrost-4-en-3-oneEdivoxetine
go.drugbank.com/drugs/DB09184InvestigationalEdivoxetine is a drug which acts as a selective norepinephrine reuptake inhibitor and is currently under development by Eli Lilly for attention-deficit hyperactivity disorder (ADHD) and as an antidepressant
Categories: Heterocyclic Compounds, 1-RingCabamiquine
go.drugbank.com/drugs/DB21477InvestigationalCabamiquine is a small molecule drug. … Falciparum Infection (CAPTURE-2)).
Categories: Heterocyclic Compounds, 2-RingαAβ–Gas6
go.drugbank.com/drugs/DB17069ExperimentalIt is made of a single chain variable fragment (scFv) of an Amyloid β (Aβ)-targeting monoclonal antibody fused with a truncated receptor binding domain of growth arrest-specific 6 (Gas6), which is a ligand … [A253203,A253208] αAβ–Gas6 is a phagocyte inducer of Aβ,[A253203] which is the main component of the amyloid plaques found in individuals with AD and is considered to contribute to the pathophysiology
2,5-Dimethoxy-4-ethylthioamphetamine
go.drugbank.com/drugs/DB13940Experimental2,5-Dimethoxy-4-ethylthioamphetamine (ALEPH-2) is a phenylisopropylamine derivative with alleged anxiolytic and hallucinogenic properties.
Categories: Serotonin 5-HT2 Receptor AgonistsSynonyms: ALEPH-2, 2,5-Dimethoxy-4-ethylthioamphetamine