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Nizubaglustat
go.drugbank.com/drugs/DB21603InvestigationalNizubaglustat is under investigation in clinical trial NCT07054515 (A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type … The usage of the INN stem '-glustat' in the name indicates that Nizubaglustat is a ceramide glucosyltransferase inhibitor.
Nevadistinel
go.drugbank.com/drugs/DB21632InvestigationalThe usage of the INN stem '-stinel' in the name indicates that Nevadistinel is a N-methyl-D-aspartate (NMDA) receptor co-agonist. … Nevadistinel is under investigation in clinical trial NCT04148391 (NYX-458 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Parkinson's Disease or Lewy Body Dementia (Cognition, Memory
Vicadrostat
go.drugbank.com/drugs/DB21693InvestigationalVicadrostat is under investigation in clinical trial NCT07064473 (A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular … The usage of the INN stem '-drostat' in the name indicates that Vicadrostat is a inhibitor of the synthesis of aldosterone and cortisol.
Ceramide NP
go.drugbank.com/drugs/DB14111InvestigationalCeramide NP is a lipid molecule included in a group of lipid molecules called ceramides. Ceramides are major lipid components in the stratum corneum of the human skin. … Ceramide 3 consists of a phytosphingosine backbone N-acylated with a saturated fatty acid (stearic acid) [A27233]. It is widely used as a moisturizer in various cosmetic and personal products.
Synonyms: Cer(t18:0/18:1n-9), N-oleoylphytosphingosineMivebresib
go.drugbank.com/drugs/DB21300InvestigationalMivebresib is under investigation in clinical trial NCT04480086 (Safety and Tolerability Study of Mivebresib Tablet Alone or in Combination With Ruxolitinib Tablet or Navitoclax Tablet in Adult Participants … The usage of the INN stem '-bresib' in the name indicates that Mivebresib is a inhibitor of the bromodomain and extra-terminal motif (BET) family of bromodomain (BRD) protein, antineoplastic.
Robenacoxib
go.drugbank.com/drugs/DB11455ExperimentalVet approvedRobenacoxib is a non-steroidal anti-inflammatory drug used in veterinary medicine for the relief of pain and inflammation in cats and dogs.
Anetumab ravtansine
go.drugbank.com/drugs/DB14809InvestigationalAnetumab ravtansine is under investigation in clinical trial NCT03455556 (Anetumab Ravtansine and Atezolizumab in Treating Participants With Advanced Non-small Cell Lung Cancer).
Osocimab
go.drugbank.com/drugs/DB14818InvestigationalOsocimab is under investigation in clinical trial NCT03276143 (Factor XIa inhibition for the prevention of venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty).
Human interleukin-2
go.drugbank.com/drugs/DB14865InvestigationalHuman interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With IL-2 and Nivo Rescue in mMEL).
Selitrectinib
go.drugbank.com/drugs/DB14896InvestigationalSelitrectinib is under investigation in clinical trial NCT03215511 (Phase 1/2 Study of LOXO-195 in Patients With Previously Treated NTRK Fusion Cancers).