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BEA-17
go.drugbank.com/drugs/DB18574ExperimentalBEA-17 is a small molecule targeted degrader of the epigenetic enzyme LSD1 and its co-factor CoREST.[L48330] It is under investigation for the treatment of glioblastoma.
CYNK-101
go.drugbank.com/drugs/DB18637InvestigationalCYNK-101 is an allogeneic human placental hematopoietic stem cell-derived natural killer (NK) cell therapy product that is genetically modified to express a variant of CD16 (CD16VP).
Synonyms: allogeneic human placental hematopoietic stem cell derived natural killer (NK) cell therapy product that is genetically modified to express a variant of CD16 (CD16VP)Zandatrigine
go.drugbank.com/drugs/DB19051InvestigationalZandatrigine is under investigation in clinical trial NCT05226780 (Extension Study to Evaluate How Safe and Tolerable NBI-921352 Is as an Adjunctive Therapy for Participants With SCN8A-DEE).
Synonyms: Benzenesulfonamide, 2-fluoro-5-methyl-4-(methyl((3s)-1-(phenylmethyl)-3-pyrrolidinyl)amino)-n-4-thiazolyl-Otamixaban
go.drugbank.com/drugs/DB06635InvestigationalOtamixaban is a novel direct Factor Xa (FXa) inhibitor. It is currently being developed by the French pharmaceutical company Sanofi-Aventis as a treatment for acute coronary syndrome.
Categories: Heterocyclic Compounds, 1-RingSolanezumab
go.drugbank.com/drugs/DB11756InvestigationalSolanezumab is under investigation for the treatment of Dementia, Alzheimers Disease, and Alzheimers Disease, Familial.
norUrsodeoxycholic acid
go.drugbank.com/drugs/DB16260InvestigationalnorUrsodeoxycholic acid is under investigation in clinical trial NCT03872921 (Norursodeoxycholic Acid vs Placebo in PSC).
Poseltinib
go.drugbank.com/drugs/DB16299InvestigationalPoseltinib is under investigation in clinical trial NCT02628028 (A Study of LY3337641 in Rheumatoid Arthritis).
Categories: Heterocyclic Compounds, 1-RingSodelglitazar
go.drugbank.com/drugs/DB16332InvestigationalSodelglitazar is under investigation in clinical trial NCT00196989 (Study in People With Type 2 Diabetes).
Phorbol 12-myristate 13-acetate diester
go.drugbank.com/drugs/DB17045InvestigationalPhorbol 12-myristate 13-acetate diester is an inducer of neutrophil extracellular traps (NETs).[A253087]
Synonyms: 12-o-tetradecanoylphorbol-13-acetateSipagladenant
go.drugbank.com/drugs/DB17080InvestigationalKW-6356 is a selective antagonist of adenosine A2A receptors developed by Kyowa Kirin.[L43822]