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Displaying results 7751 - 7760 of 10000 in total
  1. Drug

    Mivebresib

    go.drugbank.com/drugs/DB21300
    Investigational

    Mivebresib is under investigation in clinical trial NCT04480086 (Safety and Tolerability Study of Mivebresib Tablet Alone or in Combination With Ruxolitinib Tablet or Navitoclax Tablet in Adult Participants … The usage of the INN stem '-bresib' in the name indicates that Mivebresib is a inhibitor of the bromodomain and extra-terminal motif (BET) family of bromodomain (BRD) protein, antineoplastic.

  2. Drug

    MGC030

    go.drugbank.com/drugs/DB33973
    Experimental

    MGC030 is a biologic drug. MGC030 is under investigation in clinical trial NCT07822399 (A Study of MGC030 in Participants With Advanced Solid Tumors).

  3. Drug

    Mirfentanil

    go.drugbank.com/drugs/DB09175
    Experimental

    At lower doses, it antagonizes the analgesic effects of alfentanil and substitutes for naloxone in morphine-treated monkeys; however, it also reverses naloxone-precipitated withdrawal in pigeons trained … At high doses, it exhibits analgesic activity which is not fully reversed by opioid antagonists, suggesting that the drug has both opioid and non-opioid mechanisms of action.

  4. Drug

    Vanillic acid

    go.drugbank.com/drugs/DB02130
    Experimental

    It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin. (J Biotechnol 1996;50(2-3):107-13).

  5. Drug

    BMS-919373

    go.drugbank.com/drugs/DB15047
    Investigational

    BMS-919373 is under investigation in clinical trial NCT02153437 (Study of the Effects of BMS-919373 on the Electrical Activity of the Heart Using Pacemakers).

  6. Drug

    Apricitabine

    go.drugbank.com/drugs/DB12855
    Investigational

    Apricitabine has been used in trials studying the treatment of HIV Infections.

  7. Drug

    Abivertinib

    go.drugbank.com/drugs/DB15327
    Investigational

    The study is expected to be completed in March 2021.[L17398] … [L17383] It has been investigated for use in the treatment of non-small cell lung cancer (NSCLC) and B-cell malignancies.

  8. Drug

    Enrofloxacin

    go.drugbank.com/drugs/DB11404
    InvestigationalVet approved

    Due to the identification of fluoroquinolone-resistant strains of _Campylobacter_, in September 2005, the FDA withdrew the approval of enrofloxacin for its use in water to treat flocks of poultry. … Enrofloxacin is an antibiotic agent from the fluoroquinolone family produced by the Bayer Corporation. Enrofloxacin is approved by the FDA for its veterinary use.

  9. Drug

    Talsupram

    go.drugbank.com/drugs/DB09191
    Experimental

    Talsupram is a selective norepinephrine reuptake inhibitor (NRI). It was under research for the treatment of depression in 1960 and 1970 but it was never marketed.

  10. Drug

    Ufenamate

    go.drugbank.com/drugs/DB20368
    Experimental

    Ufenamate is a small molecule drug. The usage of the INN stem '-fenamate' in the name indicates that Ufenamate is a "fenamic acid" derivative.