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Temsavir
go.drugbank.com/drugs/DB14675InvestigationalCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesPegzilarginase
go.drugbank.com/drugs/DB14780ApprovedPegzilarginase is a recombinant, cobalt-substituted, and pegylated human arginase 1 enzyme therapy designed to address the underlying metabolic deficit in arginase 1 deficiency (ARG1-D). … FDA in February 2026 for the treatment of hyperargininemia in adult and pediatric patients aged 2 years and older with ARG1-D, to be used in conjunction with dietary protein restriction.
ONO-2952
go.drugbank.com/drugs/DB14802Investigationalinvestigation in clinical trial NCT01887002 (Study to Evaluate the Effects of ONO-2952 on Pain Perception Produced by Rectal Distention in Female Subjects With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)
Myrcludex B
go.drugbank.com/drugs/DB14853InvestigationalClinical Study to Assess Efficacy and Safety of 3 Doses of Myrcludex B for 24 Weeks in Combination With Tenofovir Compared to Tenofovir Alone to Suppress HBV Replication in Patients With Chronic Hepatitis D)
Olorofim
go.drugbank.com/drugs/DB15245InvestigationalOlorofim is under investigation in clinical trial NCT03340597 (Assessment of Varying Oral Dosing Regimens for F901318 in Healthy Subjects).
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 SubstratesYersinia pestis 195/p antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB15461InvestigationalYersinia pestis 195/p antigen (formaldehyde inactivated) is under investigation in clinical trial NCT02596308 (Immunogenicity and Safety of Subunit Plague Vaccine).
Synonyms: Yersinia pestis 195/p antigen (formaldehyde inactivated)Mexazolam
go.drugbank.com/drugs/DB15489InvestigationalMexazolam (CS-386) is a benzodiazepine indicated for the treatment of anxiety with or without psychoneurotic conditions. Mexazolam's structure is similar to that of other benzodiazepines such as oxazolam and cloxazolam. The use of benzod...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesLeptazoline A
go.drugbank.com/drugs/DB15551ExperimentalAlso see [Leptazoline B], [Leptazoline C], and [Leptazoline D].
Leptazoline B
go.drugbank.com/drugs/DB15552ExperimentalAlso see [Leptazoline A], [Leptazoline C], and [Leptazoline D].
Leptazoline C
go.drugbank.com/drugs/DB15553ExperimentalAlso see [Leptazoline A], [Leptazoline B], and [Leptazoline D].