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Stem-cell derived exosome vesicle products
go.drugbank.com/drugs/DB15743ExperimentalThese exosomes can also consist of VEGF and matrix metalloproteinase-9 (MMP-9) which aid in angiogenesis and tissue repair. … While many contain a conserved set of proteins, they also carry unique tissue type-specific proteins.
Alcestobart
go.drugbank.com/drugs/DB28487InvestigationalAlcestobart is under investigation in clinical trial NCT05909904 (A Study of Tislelizumab in Combination With Investigational Agents in Participants With Head and Neck Squamous Cell Carcinoma). … Alcestobart is a biologic drug.
Refanezumab
go.drugbank.com/drugs/DB14908InvestigationalRefanezumab is under investigation in clinical trial NCT00833989 (Safety Escalating Repeat IV, in Stroke Patients).
Bifikafusp alfa
go.drugbank.com/drugs/DB19185InvestigationalBifikafusp alfa is under investigation in clinical trial NCT05329792 (L19IL2/L19TNF in Skin Cancer Patients).
Synonyms: Immunoglobulin, anti-(human fibronectin ed-b domain) (synthetic human clone l19 scfv fragment) fusion protein with human interleukin 2Martinostat
go.drugbank.com/drugs/DB14979InvestigationalMartinostat is under investigation in clinical trial NCT03721211 (Imaging With [11C]Martinostat in Breast Cancer).
Fibronectin
go.drugbank.com/drugs/DB15150InvestigationalFibronectin is under investigation in clinical trial NCT01812239 (Vaginal Progesterone in Twins With Short Cervix).
ATG-101
go.drugbank.com/drugs/DB17162Investigational, while delivering enhanced anti-tumor activity, with an improved safety profile. … ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors
Synonyms: PD-L1/4-1BB bispecific antibodyAmcasertib
go.drugbank.com/drugs/DB14866InvestigationalAmcasertib is under investigation in clinical trial NCT02483247 (A Study of BBI503 in Combination With Selected Anti-Cancer Therapeutics in Adult Patients With Advanced Cancer).
APG-1387
go.drugbank.com/drugs/DB16095InvestigationalAPG-1387 is under investigation in clinical trial NCT04568265 (A Clinical Study of APG-1387 in Combination With Entecavir in Patients With Chronic Hepatitis B).
L-deprenyl-D2 C-11
go.drugbank.com/drugs/DB12650ExperimentalL-deprenyl-D2 C-11 is under investigation in clinical trial NCT01701089 (A Study of RO4602522 in Patients With Alzheimer Disease and in Healthy Volunteers).
Synonyms: (11C)L-deprenyl-D2, L-deprenyl-D2 C-11