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Displaying results 771 - 780 of 10000 in total
  1. Target

    Leukotriene B4 receptor 1

    go.drugbank.com/bio_entities/BE0003490
    TargetHumans

    Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. … Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response

    Polypeptides: Leukotriene B4 receptor 1Synonyms: G protein-coupled receptor 16, Chemoattractant receptor-like 1
  2. Target

    5-hydroxytryptamine receptor 3C

    go.drugbank.com/bio_entities/BE0009584
    TargetHumans

    Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 3CSynonyms: Serotonin receptor 3C
  3. Target

    Chemerin-like receptor 1

    go.drugbank.com/bio_entities/BE0019036
    TargetHumans

    Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1.

    Polypeptides: Chemerin-like receptor 1Synonyms: Chemokine-like receptor 1, G protein-coupled receptor DEZ
  4. Target

    Prostaglandin D2 receptor 2

    go.drugbank.com/bio_entities/BE0003561
    TargetHumans

    Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. … Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses

    Polypeptides: Prostaglandin D2 receptor 2Synonyms: G protein-coupled receptor 44, Chemoattractant receptor-homologous molecule expressed on Th2 cells
  5. Drug

    Tauroursodeoxycholic acid

    go.drugbank.com/drugs/DB08834
    ApprovedInvestigationalWithdrawn

    Tauroursodeoxycholic acid can reduce the absorption of cholesterol in the small intestine, thereby reducing the body's intake of dietary cholesterol and the body cholesterol content. … [A249080] Tauroursodeoxycholic acid is currently used in Europe to treat and prevent gallstones as a bile acid derivative.

  6. Drug

    Fostemsavir

    go.drugbank.com/drugs/DB11796
    ApprovedInvestigational

    [L14867] The discovery of gp120 as a potential target of interest in the treatment of HIV-1 infection is relatively recent, and was born out of a desire to find alternative target proteins (i.e. mechanistically … prevents the first step in the HIV-1 viral lifecycle.

  7. Drug

    Ceftazidime

    go.drugbank.com/drugs/DB00438
    ApprovedInvestigational

    [L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone or in combination with the non-β-lactam β-lactamase inhibitor [avibactam] to treat a variety of … Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding

    Products: SEFAVİS 1 G IM/IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON VE 1 AMPUL, SEFAVİS 500 MG IM/IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON VE 1 AMPUL
  8. Target

    Thyroid hormone receptor alpha

    go.drugbank.com/bio_entities/BE0003867
    TargetHumans

    Polypeptides: Thyroid hormone receptor alphaSynonyms: Nuclear receptor subfamily 1 group A member 1, Thyroid hormone receptor, alpha isoform 1 variant
  9. Target

    receptor protein-tyrosine kinase

    go.drugbank.com/bio_entities/BE0004155
    TargetHumans

    Polypeptides: receptor protein-tyrosine kinase
  10. Target

    Sulfonylurea receptor 1, Kir6.2

    go.drugbank.com/bio_entities/BE0008670
    TargetHumans

    Regulator subunit of pancreatic ATP-sensitive potassium channel (KATP), playing a major role in the regulation of insulin release. In pancreatic cells, it forms KATP channels with KCNJ11; KCNJ11 forms the channel pore while ABCC8 is requ...

    Synonyms: Sulfonylurea receptor 1