Search
Medetomidine
go.drugbank.com/drugs/DB11428ExperimentalVet approvedThe marketed product is a racemic mixture of two stereoisomers from which dexmedetomidine is the main active isomer. … Medetomidine is an intravenously available alpha-2 adrenergic agonist. The drug has been developed by Orion Pharma.
Synonyms: (±)-4-(α,2,3-trimethylbenzyl)imidazoleCategories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-2 Receptor AgonistsPerfluorodecalin
go.drugbank.com/drugs/DB16292InvestigationalSkin Removal From the Thigh - a Study in "Split Wound Design"). … Perfluorodecalin is under investigation in clinical trial NCT03668665 (Influencing Wound Healing Through the Application of Hyaluronic Acid With Perfluorodecalin and Physalis Angulata Extract After Split
Thalagen
go.drugbank.com/drugs/DB17714ExperimentalIt is being investigated for the treatment of beta-thalassemia.[L46168] … It consists of autologous CD34-positive hematopoietic progenitor cells transduced with TNS9.3.55, a lentiviral vector encoding the normal human beta-globin gene.
AVR-RD-05
go.drugbank.com/drugs/DB18631ExperimentalAVR-RD-05 is a gene therapy comprising genetically modified autologous stem cells transduced _ex vivo_ with a lentiviral vector encoding the human iduronate-2-sulfatase (IDS) enzyme. … It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII).
Synonyms: Ex vivo, lentiviral vector (LV)-mediated, genetically modified autologous cell therapy intended for the stable provision of functional human iduronate-2-sulfatase (IDS) enzyme to subjects with Hunter syndromeGiredestrant
go.drugbank.com/drugs/DB19125InvestigationalGiredestrant is under investigation in clinical trial NCT06065748 (A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With Er-positive … , Her2-negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (Pionera Breast Cancer)).
Synonyms: (1r,3r)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)-3-azetidinyl)amino)phenyl)-.beta.,.beta.-difluoro-1,3,4,9-tetrahydro-3-methyl-2h-pyrido(3,4-b)indole-2-propanol, 3-((1r,3r)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2h-pyrido(3,4-b)indol-2-yl)-2,2-difluoropropan-1-olCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingUridine diphosphate glucose
go.drugbank.com/drugs/DB01861ExperimentalServes as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which can then be incorporated into polysaccharides as galactose and glucuronic acid. … Also serves as a precursor of sucrose lipopolysaccharides, and glycosphingolipids.
Synonyms: 5'-Diphosphoglucose, Uridine-5'-DiphosphoglucoseCategories: Heterocyclic Compounds, 1-RingMarbofloxacin
go.drugbank.com/drugs/DB11426ExperimentalVet approvedMarbofloxacin is a carboxylic acid, part of the third generation of antibiotic fluoroquinolones. It is used in veterinary medicine. … A formulation of marbofloxacin combined with clotrimazole and dexamethasone is available under the name Aurizon.
Categories: 4-Quinolones, Heterocyclic Compounds, 2-RingUltevursen
go.drugbank.com/drugs/DB17835InvestigationalUltevursen is a single-stranded RNA-based oligonucleotide targeting exon 13 of the USH2A gene that encodes usherin. … It was developed by ProQR Therapeutics and is being investigated for the treatment of retinitis pigmentosa.
Choline alfoscerate
go.drugbank.com/drugs/DB04660InvestigationalA component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids. … (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules. [PubChem]
Synonyms: Glicerofosfato de colina, Glycerophosphate de cholineProducts: MEDOTİLİN 1000 MG/ 4 ML IM/IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPÜL, 3 ADETSP-8203
go.drugbank.com/drugs/DB11670InvestigationalSP-8203 has been used in trials studying the treatment of Ischemic Stroke.
Categories: Heterocyclic Compounds, 2-Ring