Ultevursen

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Ultevursen
DrugBank Accession Number
DB17835
Background

Ultevursen is a single-stranded RNA-based oligonucleotide targeting exon 13 of the USH2A gene that encodes usherin. It was developed by ProQR Therapeutics and is being investigated for the treatment of retinitis pigmentosa.

Type
Biotech
Groups
Investigational
Biologic Classification
Nucleic Acid Based Therapies
Oligonucleotides
Synonyms
Not Available
External IDs
  • QR 421a
  • QR-421
  • QR-421a
  • QR421a
  • QRX-421

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
94AC8YWE3I
CAS number
2642382-41-8

References

General References
Not Available
Not Available

Clinical Trials

Clinical Trials
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
2Not Yet RecruitingTreatmentDeaf Blind / Eye Diseases, Hereditary / Eye disorders congenital / Retinal Diseases / Retinitis Pigmentosa (RP) / Usher Syndrome Type 2 / Vision Disorders1somestatusstop reasonjust information to hide
2TerminatedTreatmentRetinitis Pigmentosa (RP) / Usher Syndrome Type 21somestatusstop reasonjust information to hide
2, 3TerminatedTreatmentDeaf Blind / Eye Diseases / Eye Diseases, Hereditary / Eye disorders congenital / Retinal Diseases / Retinitis Pigmentosa (RP) / Usher Syndrome Type 2 / Vision Disorders2somestatusstop reasonjust information to hide
1, 2CompletedTreatmentDeaf Blind / Eye Diseases / Eye Diseases, Hereditary / Eye disorders congenital / Retinal Diseases / Retinitis Pigmentosa (RP) / Usher Syndrome Type 2 / Vision Disorders1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at May 31, 2023 14:34 / Updated at July 18, 2023 22:59