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Bergapten
go.drugbank.com/drugs/DB12216InvestigationalBergapten is under investigation in clinical trial NCT00533195 (Comparison of UVA1 Phototherapy Versus Photochemotherapy for Patients With Severe Generalized Atopic Dermatitis).
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsSeviteronel
go.drugbank.com/drugs/DB12275InvestigationalSeviteronel has been used in trials studying the treatment of CRPC, Prostate Cancer, and Castration-resistant Prostate Cancer.
Categories: Cytochrome P-450 Enzyme InhibitorsSagopilone
go.drugbank.com/drugs/DB12391InvestigationalSagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast Cancer, and Breast Neoplasms, among others. It is a so-called fully synthetic epothilone and is the first such compound to be in clinic...
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsSulforaphane
go.drugbank.com/drugs/DB12422InvestigationalSulforaphane is under investigation for the treatment of Autism Spectrum Disorder. It is a naturally occurring isothiocyanate found in high concentration in a variety of broccoli.
Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 Enzyme InhibitorsKetanserin
go.drugbank.com/drugs/DB12465InvestigationalKetanserin has been investigated for the treatment of Septic Shock, Severe Sepsis, and Diabetic Foot Ulcer.
Mixtures: SUFREXAL PLobucavir
go.drugbank.com/drugs/DB12531InvestigationalLobucavir has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSAR-405838
go.drugbank.com/drugs/DB12541InvestigationalSAR405838 has been used in trials studying the treatment of Neoplasm Malignant.
Categories: P-glycoprotein substratesEtripamil
go.drugbank.com/drugs/DB12605ApprovedInvestigationalEtripamil is a nondihydropyridine, L-type calcium channel blocker. It is a fast-acting drug with a short duration of action. The nasal formulation of etripamil was first approved by the FDA on December 12, 2025 for the conversion of acut...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesBucindolol
go.drugbank.com/drugs/DB12752InvestigationalBucindolol has been investigated in Heart Failure.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesGallopamil
go.drugbank.com/drugs/DB12923InvestigationalGallopamil has been used in trials studying the treatment of Asthma.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates