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Displaying results 7871 - 7880 of 10000 in total
  1. Drug

    Duvoglustat

    go.drugbank.com/drugs/DB03206
    Investigational

    An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.

  2. Drug

    N,N-dimethylarginine

    go.drugbank.com/drugs/DB01686
    Experimental

    Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. … ADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and hence cardiovascular health.

    Synonyms: guanidino-N,N-dimethylarginine, N(G),N(G)-Dimethylarginine
  3. Drug

    Ruserontinib

    go.drugbank.com/drugs/DB21555
    Investigational

    Ruserontinib is under investigation in clinical trial NCT04716114 (A Study of SKLB1028 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory (R/R) AML With FLT3-Mutated). … The usage of the INN stem '-tinib' in the name indicates that Ruserontinib is a tyrosine kinase inhibitor.

  4. Drug

    Enbezotinib

    go.drugbank.com/drugs/DB21565
    Investigational

    Enbezotinib is under investigation in clinical trial NCT04161391 (Study of TPX-0046, A RET/SRC Inhibitor in Adult Subjects With Advanced Solid Tumors Harboring RET Fusions or Mutations). … The usage of the INN stem '-tinib' in the name indicates that Enbezotinib is a tyrosine kinase inhibitor.

  5. Drug

    QRX-411

    go.drugbank.com/drugs/DB17868
    Experimental

    It addresses the underlying cause of Usher syndrome due to the c.7595-2144A>G mutation in the _USH2A_ gene.[L46777] … QRX-411 is a first-in-class RNA-based oligonucleotide designed to restore wild-type USH2A mRNA, leading to the production of the functional USH2A protein.

  6. Drug

    Spermidine

    go.drugbank.com/drugs/DB03566
    Investigational

    It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures.

    Synonyms: N-(3-Aminopropyl)-1,4-butane-diamine, N-(3-aminopropyl)butane-1,4-diamine
  7. Drug

    Reparixin

    go.drugbank.com/drugs/DB12614
    Investigational

    1, and Pancreatic Islet Transplantation in Type 1 Diabetes Mellitus. … Reparixin has been used in trials studying the treatment and prevention of Breast Cancer, Metastatic Breast Cancer, Pancreatectomy for Chronic Pancreatitis, Islet Transplantation in Diabetes Mellitus Type

  8. Drug

    Plamotamab

    go.drugbank.com/drugs/DB18944
    Investigational

    Plamotamab is under investigation in clinical trial NCT05328102 (Phase 2 Study of Plamotamab Combined With Tafasitamab Plus Lenalidomide Versus Tafasitamab Plus Lenalidomide in Relapsed or Refractory (

  9. Drug

    161Tb-PSMA-1

    go.drugbank.com/drugs/DB33964
    Experimental

    161Tb-PSMA-1 is a small molecule drug. 161Tb-PSMA-1 is under investigation in clinical trial NCT07828249 (Phase I Study Evaluating 161Tb-PSMA Therapy in Adult Patients With Metastatic Clear Cell Renal

  10. Drug

    β-Hydroxythiofentanyl

    go.drugbank.com/drugs/DB09170
    ExperimentalIllicit

    β-Hydroxythiofentanyl is an analgesic of the _opioid_ class. This drug is an analog of fentanyl, a potent opioid.