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Cetrorelix
go.drugbank.com/drugs/DB00050ApprovedInvestigationalCetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH).
Products: CETROTIDE 250 MCG ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 7 ADET, CETROTIDE 3 MG.Iloprost
go.drugbank.com/drugs/DB01088ApprovedInvestigational[A263326] Iloprost consists of a mixture of the 4R and 4S diastereoisomers at a ratio of approximately 53:47.[L50146] It is a potent vasodilator with reported anti-thrombotic properties. … Iloprost is an analog of prostacyclin (PGI2; epoprostenol), an endogenous prostanoid mainly produced in the vascular endothelium. It is more stable than prostacyclin, which is short-lived.
Synonyms: (5E)-[3aS,4R,5R,6aS)-5-Hydroxy-4-[(1E)-(3S,4RS)-3-hydroxy-4-methyloct-1-en-6-ynyl]-hexahydropentalen-2(1H)-ylidene]pentanoic acid, PENTANOIC ACID, 5-((3AS,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-((1E,3S)-3-HYDROXY-4-METHYL-1-OCTEN-6-YNYL)-2(1H)-PENTALENYLIDENE)-, (5E)-Products: İVİLOST 20 MCG/2 ML İV İNFÜZYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 5 AMPUL, DIVODIN 20 MCG/ML I.V İNFÜZYONLUK ÇÖZELTİ, 5 ADETMaribavir
go.drugbank.com/drugs/DB06234ApprovedInvestigational[L39327] The drug was also approved by Health Canada in September 2022 [L43262] and by European Commission in November 2022.[L44411] … [A242557] Maribavir is novel in that it instead targets the CMV pUL97 kinase, thereby providing an effective alternative treatment option in cases of resistant infections.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: Livtencity 200 mg Film Kaplı Tablet (112 (56'lık 2 şişe) Adet), Livtencity 200 mg Film Kaplı Tablet (28 Adet)Verapamil
go.drugbank.com/drugs/DB00661ApprovedInvestigational[L8791] Verapamil is administered as a racemic mixture containing equal amounts of the S- and R-enantiomer, each of which is pharmacologically distinct - the S-enantiomer carries approximately 20-fold … into therapy in the early 1960s.
Mixtures: VERAPIN 180 MG/2 MG FILM KAPLI TABLET, 28 ADET, VERACOMB MR 180/2 MG KAPSÜL, 28 ADETCategories: MATE 2 Inhibitors, MATE 1 InhibitorsDrospirenone
go.drugbank.com/drugs/DB01395ApprovedInvestigationalDrospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with [Ethinyl estradiol]. … [A182543,A182552] In 2012, however, a safety statement by the FDA concluded that the increase in the risk of thromboembolism resulting from the use of drospirenone remains unclear, as studies regarding
Mixtures: ANGELIQ 1 MG/2 MG FILM KAPLI TABLET, 28 ADET, Angeliq 1 mg/2 mg FilmtablettenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSumatriptan
go.drugbank.com/drugs/DB00669ApprovedInvestigational[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. … [A179761] Sumatriptan was granted FDA approval on 28 December 1992.[L6805]
Mixtures: TRASS® TABLETA RECUBIERTA, TRASS® TABLETA RECUBIERTACategories: Serotonin 5-HT1 Receptor Agonists, Selective Serotonin 5-HT1 Receptor AgonistsInsulin aspart
go.drugbank.com/drugs/DB01306ApprovedInvestigationalDue to its duration of action of around 5 hours, NovoRapid is considered "bolus insulin" as it provides high levels of insulin in a short period of time to mimic the release of endogenous insulin from … Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.
Mixtures: RYZODEG PENFİLL 100 U/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KARTUŞ, 5 ADET, RYZODEG FLEXTOUCH 100 U/ML ENJEKSİYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 5 ADETCategories: Drugs Used in Diabetes, Cytochrome P-450 CYP1A2 InducersPrednisolone phosphate
go.drugbank.com/drugs/DB14631ApprovedInvestigationalVet approved[A187463] Prednisolone phosphate was granted FDA Approval on 19 December 1973.[L14144] … Prednisolone phosphate is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.
Mixtures: OFTALETYC® NFCategories: P-glycoprotein inducers, Cytochrome P-450 CYP2A6 InducersPralatrexate
go.drugbank.com/drugs/DB06813ApprovedInvestigational[A246703] Pralatrexate was approved by the FDA on September 24, 2009. … Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma [L37674].
Categories: Heterocyclic Compounds, 2-RingSynonyms: (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid, N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acidPolymyxin B
go.drugbank.com/drugs/DB00781ApprovedInvestigationalVet approvedPolymyxin B was discovered in the 1940s[A176429]. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes[A176426]. … Polymyxin B has a narrow therapeutic index and so its use is limited and unlikely to be used first line[A176429].
Synonyms: Polymyxin B, Polimixina BInternational brands: Polomyxin B