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Displaying results 781 - 790 of 6948 in total
  1. Drug

    Retlirafusp alfa

    go.drugbank.com/drugs/DB17517
    Investigational

    Synonyms: programmed death-ligand 1) (human-mus musculus monoclonal SHR-1316 .gamma.4-chain) fusion protein with peptide linker ((ggggs)4g) fusion protein with 20-136-type II transforming growth factor .beta. receptor
  2. Drug

    Acimtamig

    go.drugbank.com/drugs/DB18674
    Investigational

    Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody construct.

    Synonyms: Immunoglobulin, anti-(human FcγRIIIa receptor) (human heavy chain V-D-J region) fusion protein with peptide linker (GGS)3 fusion protein with immunoglobulin anti-(human CD30 antigen) (human-Mus musculus
  3. Drug

    Polyethylene glycol 400

    go.drugbank.com/drugs/DB11077
    ApprovedInvestigational

    PEGylation occurs when PEGs are attached to numerous protein medications, allowing for greater solubility for selected drugs. … In addition, PEG is available as a bowel preparation for colonoscopy procedures and as a laxative [L1788].

    Mixtures: Visine for Red Eye Cool, Visine for Red Eye Workplace
  4. Drug

    Fostemsavir

    go.drugbank.com/drugs/DB11796
    ApprovedInvestigational

    [L14867] The discovery of gp120 as a potential target of interest in the treatment of HIV-1 infection is relatively recent, and was born out of a desire to find alternative target proteins (i.e. mechanistically … orthogonal therapies) for the treatment of HIV-1 patients with resistant infections.

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
  5. Drug

    Pyridoxine

    go.drugbank.com/drugs/DB00165
    ApprovedInvestigationalNutraceuticalVet approved

    Pyridoxine is used medically for the treatment of vitamin B6 deficiency and for the prophylaxis of isoniazid-induced peripheral neuropathy (due to [DB00951]'s mechanism of action which competitively inhibits … It is also used in combination with [DB00366] (as the commercially available product Diclectin) for the treatment of nausea and vomiting in pregnancy.

    Mixtures: Se-Tan DHA, Se-Tan DHACategories: Antiinfectives for Systemic Use, Drugs for Treatment of Tuberculosis
  6. Drug

    Naproxen

    go.drugbank.com/drugs/DB00788
    ApprovedInvestigationalVet approved

    Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. … [A179098] Given its overall tolerability and effectiveness, naproxen can be considered a first line treatment for a variety of clinical situations requiring analgesia.

    Categories: Topical Products for Joint and Muscular Pain, Antiinflammatory Products for Vaginal AdministrationProducts: Naproxen All day relief for pain, Naproxen Caplets All day relief for pain
  7. Drug

    Anthralin

    go.drugbank.com/drugs/DB11157
    Approved

    The chemical structure of anthralin allows for dual solubility, permitting the compound to be absorbed well through the epidermis [A27276]. … It is a main active ingredient in topical skin formulations for the treatment of psoriasis. Various formulations of the drug are available, including solutions, foams, and shampoos [L1979].

    Categories: Antipsoriatics for Topical Use
  8. Drug

    Bromhexine

    go.drugbank.com/drugs/DB09019
    ApprovedInvestigational

    Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. … [A233240] Recently, bromhexine and its metabolite [ambroxol] have garnered interest for the potential prevention and treatment of COVID-19 due to their interactions with cell receptors in the lungs.

  9. Drug

    Hydroxychloroquine

    go.drugbank.com/drugs/DB01611
    ApprovedInvestigational

    [L8072] A recent study reported a fatality in the group being treated with hydroxychloroquine for COVID-19.[A192546] … [A183092] Chloroquine and hydroxychloroquine are both being investigated for the treatment of SARS-CoV-2.

  10. Drug

    Ketoprofen

    go.drugbank.com/drugs/DB01009
    ApprovedInvestigationalVet approved

    Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.

    Categories: Topical Products for Joint and Muscular Pain, Antiinflammatory Preparations, Non-Steroids for Topical UseProducts: Ketosol 100mg/ml Solution for injection