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Desipramine
go.drugbank.com/drugs/DB01151ApprovedSecondary amine TCAs, such as desipramine and nortriptyline, are more potent inhibitors of norepinephrine reuptake than tertiary amine TCAs, such as amitriptyline and doxepine. … Desipramine exerts less anticholinergic and sedative side effects compared to tertiary amine TCAs, such as amitriptyline and clomipramine.
Synonyms: 5-(γ-methylaminopropyl)iminodibenzyl, 5-(gamma-methylaminopropyl)iminodibenzylCategories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsLanreotide
go.drugbank.com/drugs/DB06791ApprovedInvestigationalLanreotide was first approved for use in the United States by the FDA on August 30, 2007. … Lanreotide is manufactured by the company, _Ipsen Pharmaceuticals_ as lanreotide acetate, and marketed as _Somatuline_.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: Mytolac 120 mg Injektionslösung in einer Fertigspritze, Somatuline Autogel 120 mg - Injektionslösung in einer FertigspritzeFlucytosine
go.drugbank.com/drugs/DB01099ApprovedInvestigationalA fluorinated cytosine analog that is used as an antifungal agent.
Synonyms: 5-FC, 5-FluorocytosineProducts: FLUSYNERG® 10 MG/ML SOLUCIÓN INYECTABLE, โทซีน (500 มก.แคปซูล)Hydroxyethyl Starch
go.drugbank.com/drugs/DB09106ApprovedInvestigationalHydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume. HES is a general term and can be sub-classified acc...
Mixtures: VOLUVEN % 6 500 ML SOLUSYON, ISOHES %6 (SETLI) 500 ML SOLUSYONProducts: HAES-STERIL %10 500 ML SOLUSYON, BIOHES %10 INTRAVENOZ 500 ML SOLUSYON SETLI SISECarbetocin
go.drugbank.com/drugs/DB01282ApprovedInvestigationalCarbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.
Products: PABAL 100 MCG/ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 5 ADET, KARPAVER 100 MCG/1 ML I.V./I.M. ENJEKSİYONLUK ÇÖZELTİ, 5 ADETSelegiline
go.drugbank.com/drugs/DB01037ApprovedInvestigationalVet approvedA selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: MOVERDIN 5 MG TABLET, 100 ADET, SELEGILIN-NEURAX 10 MGLorlatinib
go.drugbank.com/drugs/DB12130ApprovedInvestigationalinclude lorlatinib as a first-line treatment option in advanced ALK-positive NSCLC. … Lorlatinib is a third-generation ALK tyrosine kinase inhibitor (TKI) for patients with ALK-positive metastatic non-small cell lung cancer[L39905] which was first approved by the US FDA in November of 2018
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersProducts: LORBRENA® 100 MG, LORVIQUA (TABLETS 100 MG)Galantamine
go.drugbank.com/drugs/DB00674ApprovedInvestigational[A1018] First characterized in the early 1950s, galantamine is a tertiary alkaloid that was extracted from botanical sources, such as _Galanthus nivalis_. … [A201968] Galantamine was first studied in paralytic and neuropathic conditions, such as myopathies and postpolio paralytic conditions, and for reversal of neuromuscular blockade.
Mixtures: GALNORA 8MG + 16MG HKP RET, GALNORA 8MG + 16MG HKP RETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCitric acid
go.drugbank.com/drugs/DB04272ApprovedInvestigationalNutraceuticalVet approvedThe salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. … Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020.
Mixtures: ALKA-SELTZER 324 MG/965 MG/1744 MG EFERVESAN TABLET, 10 ADET, PICOPREP 10 MG / 3,5 G /12 G ORAL ÇÖZELTI IÇIN TOZ, 2 SAŞEProducts: Citracid-50, bdr Re-action natural low base skin refiner exfoliation essenceMontelukast
go.drugbank.com/drugs/DB00471ApprovedInvestigationalsince become available as a generic and as a brand name product. … Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair.
Mixtures: BROCRIPTIN® 10 MG/ 5 MG, LEPIXOS 5 MG/10 MG FILM TABLET ,30 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inducers