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Displaying results 7891 - 7900 of 10000 in total
  1. Drug

    D2C7 immunotoxin

    go.drugbank.com/drugs/DB17540
    Investigational

    D2C7-IT is under investigation in clinical trial NCT04160494 (D2C7-IT With Atezolizumab for Recurrent Gliomas). … D2C7 immunotoxin (D2C7-IT) is an investigational dual-specific monoclonal antibody targeting EGFRwt and EGFRvIII with a genetically engineered form of the _Pseudomonas exotoxin_, PE38-KDEL.

    Synonyms: D2C7-IT
  2. Drug

    Ethanolamine

    go.drugbank.com/drugs/DB03994
    Investigational

    A viscous, hygroscopic amino alcohol with an ammoniacal odor. It is widely distributed in biological tissue and is a component of lecithin. … It is used as a surfactant, fluorimetric reagent, and to remove CO2 and H2S from natural gas and other gases.

  3. Drug

    Pamiparib

    go.drugbank.com/drugs/DB14769
    Investigational

    Pamiparib is under investigation in clinical trial NCT03933761 (Pamiparib in Fusion Positive, Reversion Negative High Grade Serous Ovarian Cancer or Carcinosarcoma With BRCA1/2 Gene Mutations If Progression … on Substrate Poly ADP Ribose Polymerase Inhibitbor (PARPI) or Chemotherapy).

  4. Drug

    Pyruvaldehyde

    go.drugbank.com/drugs/DB03587
    Experimental

    An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. … It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals. [PubChem]

  5. Drug

    FK-960

    go.drugbank.com/drugs/DB06465
    Experimental

    Synonyms: N-(4-Acetyl-1-piperazinyl)-4-fluorobenzamide
  6. Drug

    Mangostin

    go.drugbank.com/drugs/DB14371
    Investigational

    Mangostin is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  7. Drug

    Pumice

    go.drugbank.com/drugs/DB14374
    Investigational

    Pumice is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  8. Drug

    Fusafungine

    go.drugbank.com/drugs/DB08965
    ApprovedWithdrawn

    Fusafungine is an antibiotic from Fusarium lateririum, and is used for the treatment of respiratory infections.

  9. Drug

    Nafithromycin

    go.drugbank.com/drugs/DB16246
    Investigational

    Nafithromycin is under investigation in clinical trial NCT02903836 (Phase II Study of Oral Nafithromycin in CABP).

  10. Drug

    Tefidsogene civaparvovec

    go.drugbank.com/drugs/DB16789
    Investigational

    It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes … Developed by Sangamo Therapeutics, tefidsogene civaparvovec is being investigated in mucopolysaccharidosis type II.[A258789, L45949]

    Synonyms: EXONS 2-9 FROM HIDS AND A SPLICE ACCEPTOR SITE (SA), A RECOMBINANT NON-REPLICATING ADENO-ASSOCIATED VIRUS TYPE 2/6 (RAAV REP2-CAP6) VECTOR, WHICH CONTAINS A PROMOTER-LESS HUMAN IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS