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Displaying results 7901 - 7910 of 10000 in total
  1. Drug

    Spartalizumab

    go.drugbank.com/drugs/DB14892
    Investigational

    Spartalizumab is under investigation in clinical trial NCT02605967 (Safety and Efficacy Study of PDR001 in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma).

    Categories: Amino Acids, Peptides, and Proteins
  2. Drug

    Ulinastatin

    go.drugbank.com/drugs/DB12038
    Investigational

    Ulinastatin has been investigated for the prevention of Cardiovascular Disease and Adverse Reaction to Drug.

    Categories: Blood and Blood Forming Organs, Amino Acids, Peptides, and Proteins
  3. Drug

    Ciraparantag

    go.drugbank.com/drugs/DB15199
    Investigational

    Ciraparantag is under investigation in clinical trial NCT01826266 (Effects of a Double-Blind, Single Dose of PER977 Administered Alone, and Following a Single Dose of Edoxaban).

    Categories: Amino Acids, Peptides, and Proteins
  4. Drug

    Distigmine

    go.drugbank.com/drugs/DB13694
    Investigational

    It is an anticholinergic drug and long-acting reversible carbamate cholinesterase inhibitor that binds directly and competitively to the agonist binding sites of muscurinic receptors. … Distigmine is available in several countries as a treatment of underactive detrusor and voiding dysfunction in the urinary tract where the active ingredient is distigmine bromide.

  5. Drug

    Teglarinad chloride

    go.drugbank.com/drugs/DB05217
    Investigational

    In vivo, apoptosis inducer GMX1777 is rapidly converted into GMX1778 through hydrolytic cleavage of a carbonate ester bond. … Although the exact mechanism of action has yet to be fully elucidated, GMX1778 appears to antagonize nuclear factor-kappa B (NF-kB) transcription, resulting in the induction of tumor cell apoptosis.

  6. Drug

    Avasopasem manganese

    go.drugbank.com/drugs/DB16354
    Investigational

    [L27246, L27256] This drug has potential application for radiation-induced esophagitis and oral mucositis, in addition to being currently tested against COVID-19. … Avasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide dismutase (SOD) being investigated for the reduction of radiation-induced severe oral mucositis.

  7. Drug

    GC-376 free acid

    go.drugbank.com/drugs/DB15796
    Experimental

    GC-376 is a 3C-like protease (3CL<sup>pro</sup> or M<sup>pro</sup>) inhibitor that stops the cleavage and activation of functional viral proteins required for replication and transcription in host cells … In addition, GC-376 displays potent activity against various coronaviruses such as feline, ferret, and mink M<sup>pro</sup> coronavirus[A219026,A219031,A219036,A219041].

    Categories: Amino Acids, Peptides, and Proteins
  8. Drug

    1alpha-Hydroxyvitamin D5

    go.drugbank.com/drugs/DB13097
    Investigational

    1alpha-Hydroxyvitamin D5 (CARD-024) has been used in trials studying the treatment of Drug Safety and Heart; Disease, Activity.

    Categories: Vitamin D and Analogues
  9. Drug

    Deltamethrin

    go.drugbank.com/drugs/DB13600
    Experimental

    Categories: Compounds used in a research, industrial, or household setting, Insecticides and Repellents
  10. Drug

    Epanolol

    go.drugbank.com/drugs/DB13757
    Experimental

    Epanolol is an beta blocker.