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Abetimus
go.drugbank.com/drugs/DB06662InvestigationalAbetimus was developed by La Jolla Pharmaceuticals as an immunosuppressant but was never marketed in American or Europe despite application for marketing authorization in the mid-2000s.
Gimatecan
go.drugbank.com/drugs/DB06721InvestigationalGimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative.
Synonyms: (4S)-4-ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1-H-pyrano[3',4':6,7]-indolizino-[1,2-b]-quinoline-11-carbaldehyde O-(tert-butyl)-(E)-oxime, (4S)-11-[(E)-(tert-butoxyimino)methyl]-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dioneAceclofenac
go.drugbank.com/drugs/DB06736ApprovedIt is a more commonly prescribed drug in Europe. … Aceclofenac is also reported to be effective in other painful conditions such as dental and gynaecological conditions [A19672].
Mixtures: ZERODOL PCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesKetobemidone
go.drugbank.com/drugs/DB06738InvestigationalKetobemidone is a powerful opioid analgesic. It also has some NMDA-antagonist properties. This makes it useful for some types of pain that don't respond well to other opioids. … The most commonly cited equalisation ratio for analgesic doses is 25 mg of ketobemidone hydrobromide to 60 mg of morphine hydrochloride or sulfate and circa 8 mg of ketobemidone by injection.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesSeratrodast
go.drugbank.com/drugs/DB06739ExperimentalSeratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 InhibitorsGinkgolide A
go.drugbank.com/drugs/DB06743ExperimentalNutraceuticalGinkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and immunological disorders.
Synonyms: Ginkgolide-AGinsenoside C
go.drugbank.com/drugs/DB06748ExperimentalNutraceuticalCategories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 Enzyme InhibitorsAlcaftadine
go.drugbank.com/drugs/DB06766ApprovedAlcaftadine is a H1 histamine receptor antagonist indicated for the prevention of itching associated with allergic conjunctivitis. This drug was approved in July 2010.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingProducts: LASTACAFT®, LASTACAFT % 0,25 GÖZ DAMLASI, ÇÖZELTİ, 1 ADETBenzyl alcohol
go.drugbank.com/drugs/DB06770ApprovedInvestigationalMixtures: Itch-X, Itch XCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesHuman calcitonin
go.drugbank.com/drugs/DB06773Approved[A32099] It is constituted as a 32-amino acid single chain polypeptide structure that gets secreted as a regulatory agent in calcium-phosphorus metabolism. … Calcitonin was first discovered in isolated parathyroid tissue as a substance with a serum-calcium-lowering effect.