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Displaying results 7971 - 7980 of 10000 in total
  1. Target

    Protein-tyrosine kinase 2-beta

    go.drugbank.com/bio_entities/BE0000871
    TargetHumans

    Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. … Regulates cytoskeleton rearrangement and cell spreading in T-cells, and contributes to the regulation of T-cell responses.

    Synonyms: CAK-beta
  2. Drug

    Peficitinib

    go.drugbank.com/drugs/DB11708
    Investigational

    Peficitinib has been used in trials studying the treatment and basic science of Psoriasis, Pharmacodynamics, Drug Interactions, Colitis, Ulcerative, and RHEUMATOID ARTHRITIS, among others.

    Categories: Antineoplastic and Immunomodulating Agents
  3. Drug

    Ocaratuzumab

    go.drugbank.com/drugs/DB17359
    Investigational

    Ocaratuzumab is a humanized monoclonal antibody directed against CD20. It is being investigated for cancers and autoimmune disorders.

    Categories: Amino Acids, Peptides, and Proteins
  4. Drug

    Edifoligide

    go.drugbank.com/drugs/DB06556
    Investigational

    Categories: Nucleic Acids, Nucleotides, and Nucleosides
  5. Drug

    Methyl red

    go.drugbank.com/drugs/DB08209
    Experimental

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Synephrine

    go.drugbank.com/drugs/DB09203
    Investigational

    While the compounds share some chemical and pharmacological similarities, they are in fact distinct chemical entities. … It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer acting adrenergic effects compared to norepinephrine.

    Categories: Adrenergic and Dopaminergic Agents, Decongestants and Antiallergics
  7. Drug

    Nisevokitug

    go.drugbank.com/drugs/DB17561
    Investigational

    and Efficacy of Novel Ruxolitinib Combinations in Myelofibrosis Patients). … Nisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety

    Categories: Amino Acids, Peptides, and Proteins
  8. Drug

    Tomaralimab

    go.drugbank.com/drugs/DB15415
    Investigational

    Tomaralimab is under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and Efficacy of OPN-305 in Preventing Delayed Renal Graft Function).

    Categories: Amino Acids, Peptides, and Proteins
  9. Drug

    NF-kappaB Decoy

    go.drugbank.com/drugs/DB05559
    Investigational

    Categories: Nucleic Acids, Nucleotides, and Nucleosides
  10. Drug

    Thiostrepton

    go.drugbank.com/drugs/DB11467
    InvestigationalVet approved

    Thiostrepton is a natural product of the ribosomally synthesized and post-translationally modified peptide class. … Thiostrepton is a natural cyclic oligopeptide antibiotic, derived from several strains of streptomycetes including Streptomyces azureus and Streptomyces laurentii.

    Categories: Amino Acids, Peptides, and Proteins