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Displaying results 7981 - 7990 of 10000 in total
  1. Drug

    Sitofibrate

    go.drugbank.com/drugs/DB21192
    Experimental

    The usage of the INN stem '-fibrate' in the name indicates that Sitofibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist. … Sitofibrate is a small molecule drug.

  2. Drug

    Zatonacaftor

    go.drugbank.com/drugs/DB21625
    Experimental

    The usage of the INN stem '-caftor' in the name indicates that Zatonacaftor is a Cystic fibrosis transmembrane regulator (CFTR) protein modulator, corrector, and amplifier. … Zatonacaftor is a small molecule drug.

  3. Drug

    Lanabecestat

    go.drugbank.com/drugs/DB14814
    Investigational

    Lanabecestat is under investigation in clinical trial NCT03499041 (A Study of LY3314814 in Participants With Liver Impairment).

  4. Drug

    BP-14979

    go.drugbank.com/drugs/DB16302
    Investigational

    BP-14979 is under investigation in clinical trial NCT01785147 (Efficacy and Safety of BP1.4979 in Smoking Cessation).

  5. Drug

    Apratastat

    go.drugbank.com/drugs/DB13020
    Investigational

    Tmi 005 is under investigation in clinical trial NCT00095342 (Study Evaluating TMI-005 in Active Rheumatoid Arthritis).

  6. Drug

    KRN-5500

    go.drugbank.com/drugs/DB15215
    Investigational

    KRN-5500 is under investigation in clinical trial NCT00002923 (KRN5500 in Treating Patients With Metastatic Solid Tumors).

  7. Drug

    Oplunofusp

    go.drugbank.com/drugs/DB15313
    Investigational

    DAS-181 is under investigation in clinical trial NCT00527865 (Single Dose Escalating Study of DAS181 in Adults).

  8. Drug

    Sulbutiamine

    go.drugbank.com/drugs/DB13416
    Investigational

    The chronic administration of the drug has demonstrated to improve long term memory formation in mice. … It is highly lipophilic, allowing it to cross the blood-brain barrier more easily than other thiamine derivatives.

  9. Drug

    Deferitazole

    go.drugbank.com/drugs/DB13120
    Investigational

    It has been used in trials studying the treatment and basic science of Beta-thalassemia, Hepatic Impairment, Impaired Renal Function, Transfusional Iron Overload, and Iron Overload Due to Repeated Red … Deferitazole is an iron chelator.

  10. Drug

    Zeteletinib

    go.drugbank.com/drugs/DB21491
    Investigational

    Zeteletinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Zeteletinib is a tyrosine kinase inhibitor. … Zeteletinib is under investigation in clinical trial NCT03780517 (Safety, Efficacy, and Tolerability of BOS172738 in Patients With Advanced Rearranged During Transfection (RET) Gene-Altered Tumors).