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Ursodeoxycholic acid
go.drugbank.com/drugs/DB01586ApprovedInvestigational[A256272] Due to its hydrophilicity, UDCA is less toxic than [cholic acid] or [chenodeoxycholic acid]. … Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 Enzyme InducersProducts: PRESTALIX AU, Urso DSDiltiazem
go.drugbank.com/drugs/DB00343ApprovedInvestigational[T28] Being a potent vasodilator, diltiazem is used clinically as an antihypertensive, anti-arrhythmic, and as an anti-anginal agent [L6289] for the management of cardiovascular conditions such as hypertension … Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsSynonyms: d-cis-diltiazemQuetiapine
go.drugbank.com/drugs/DB01224ApprovedInvestigationalIt is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such as [clozapine] and [olanzapine].[A2189] … [L8546] Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment.
Categories: Dopamine D2 Receptor Antagonists, Cytochrome P-450 SubstratesProducts: Nu-quetiapine, QUETIAPINA DR. REDDY'SVerapamil
go.drugbank.com/drugs/DB00661ApprovedInvestigationalgreater potency than the R-enantiomer, but is metabolized at a higher rate. … [L8791] Verapamil is administered as a racemic mixture containing equal amounts of the S- and R-enantiomer, each of which is pharmacologically distinct - the S-enantiomer carries approximately 20-fold
Mixtures: VERAPIN 180 MG/2 MG FILM KAPLI TABLET, 28 ADET, VERACOMB MR 180/2 MG KAPSÜL, 28 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesTorasemide
go.drugbank.com/drugs/DB00214ApprovedInvestigationalTorasemide is a high-ceiling loop diuretic.[A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent.
Categories: Increased Diuresis at Loop of Henle, Cytochrome P-450 SubstratesSynonyms: 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)ureaOxycodone
go.drugbank.com/drugs/DB00497ApprovedIllicitInvestigational[Label] The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.[L6460] … for an extended period.
Mixtures: Nu-oxycodone/acet, TARGIN ® 20 MG / 10 MG TABLETAS DE LIBERACIÓN PROLONGADACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesDextromethorphan
go.drugbank.com/drugs/DB00514ApprovedInvestigationalDextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse.
Synonyms: DM, D-methorphanInternational brands: Benylin DMLevetiracetam
go.drugbank.com/drugs/DB01202ApprovedInvestigationalmake it a desirable choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and a propensity for involvement in drug interactions. … Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders.
Products: Nu-levetiracetam, LEVETIRACE AL 100 MG/MLSumatriptan
go.drugbank.com/drugs/DB00669ApprovedInvestigationalSumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.
Categories: Monoamine Oxidase A SubstratesProducts: Nu-sumatriptan, Ag-sumatriptanDesvenlafaxine
go.drugbank.com/drugs/DB06700ApprovedInvestigational[A261271] Desvenlafaxine has a very similar pharmacological, efficacy, and safety profile as [venlafaxine]. … [L6016,A261271] MDD is a highly prevalent psychiatric disorder, with a lifetime prevalence estimate of 16% in the US alone and 12.8% in Europe.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: EFEXOR® XR 150 MG. CAPSULAS DE LIBERACIÓN PROLONGADA, Ag-desvenlafaxine