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Riociguat
go.drugbank.com/drugs/DB08931ApprovedInvestigationalwith group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for the treatment of patients with inoperable CTEPH (chronic thromboembolic pulmonary hypertension), or persistent/recurrent PH
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: Methyl N-[4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methyl-carbaminatePalladium Pd-103
go.drugbank.com/drugs/DB15016ExperimentalPalladium Pd-103 is under investigation in clinical trial NCT00247312 (Pd-103 Dose De-Escalation for Early Stage Prostate Cancer: A Prospective Randomized Trial).
Zimlovisertib
go.drugbank.com/drugs/DB15143InvestigationalPF-06650833 is under investigation in clinical trial NCT02609139 (Study to Evaluate Pharmacokinetics of A Modified Release Formulation of PF-06650833 in Healthy Subjects).
PF-06821497
go.drugbank.com/drugs/DB14799InvestigationalPF-06821497 is under investigation in clinical trial NCT03460977 (PF-06821497 Treatment Of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma).
PF-04418948
go.drugbank.com/drugs/DB12024InvestigationalPf 04418948 is under investigation in clinical trial NCT01002963 (A Study To Investigate The Safety And Toleration Of A Single Dose Of PF-04418948 In Healthy Volunteers).
Acetylsalicylic acid
go.drugbank.com/drugs/DB00945ApprovedInvestigationalVet approvedAlso known as Aspirin, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platele...
Mixtures: Adalat XL Plus, Adalat XL PlusCategories: P-glycoprotein inducers, P-glycoprotein substratesSodium aurothiomalate
go.drugbank.com/drugs/DB09276ApprovedWithdrawnGold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold Sodium Thiomalate per mL.
Sirolimus
go.drugbank.com/drugs/DB00877ApprovedInvestigationalSirolimus, also known as rapamycin, is a macrocyclic lactone antibiotic produced by bacteria Streptomyces hygroscopicus, which was isolated from the soil of the Vai Atari region of Rapa Nui (Easter Island). It was first isolated and iden...
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: P-HYSPLAN, RAPAMUNE 1 MG/ML 60 ML ORAL SOLUSYONLowbush blueberry
go.drugbank.com/drugs/DB14229InvestigationalIngredient used in over-the-counter medications.
Ivermectin
go.drugbank.com/drugs/DB00602ApprovedInvestigationalVet approvedIvermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mi...
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: IMECTIN-2 Oral Solution 20mg/ml, IVERMECTINA6MG/ML SOLUCION ORAL