PF-06650833

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name: PF-06650833
DrugBank Accession Number: DB15143
Background: PF-06650833 is under investigation in clinical trial NCT02609139 (Study to Evaluate Pharmacokinetics of A Modified Release Formulation of PF-06650833 in Healthy Subjects).
Type: Small Molecule
Groups: Investigational
Structure: 3D
MOL SDF 3D-SDF PDB SMILES InChI

Similar Structures
Structure for PF-06650833 (DB15143)
Synonyms: Not Available

Indication: Not Available
Reduce drug development failure rates
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Pharmacodynamics: Not Available
Mechanism of action: Not Available
Absorption: Not Available
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Not Available
Half-life: Not Available
Clearance: Not Available
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Toxicity: Not Available
Pathways: Not Available
Pharmacogenomic Effects/ADRs: Not Available

Drug Interactions: This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions: Not Available

UNII: S3F315JJXI
CAS number: 1817626-54-2
InChI Key: JKDGKIBAOAFRPJ-ZBINZKHDSA-N
InChI: InChI=1S/C18H20FN3O4/c1-3-10-13(22-17(24)15(10)19)8-26-18-11-7-14(25-2)12(16(20)23)6-9(11)4-5-21-18/h4-7,10,13,15H,3,8H2,1-2H3,(H2,20,23)(H,22,24)/t10-,13+,15-/m0/s1
IUPAC Name: 1-{[(2S,3S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide
SMILES: CC[C@H]1[C@@H](COC2=C3C=C(OC)C(=CC3=CC=N2)C(N)=O)NC(=O)[C@H]1F

General References

Not Available

External Links

PDB Entries

5uiu

Clinical Trials

Phase	Status	Purpose	Conditions	Count
2	Completed	Treatment	Acne Inversa	1
2	Completed	Treatment	Rheumatoid Arthritis	2
2	Recruiting	Treatment	Coronavirus Disease 2019 (COVID‑19) / COVID-19 Pneumonia	1
2	Terminated	Treatment	Coronavirus Disease 2019 (COVID‑19)	1
1	Completed	Basic Science	Healthy Subjects (HS)	5
1	Completed	Other	Healthy Subjects (HS)	1
1	Completed	Treatment	Healthy Subjects (HS)	1

State

Not Available

Experimental Properties

Not Available

Predicted Properties

Predicted ADMET Features

Not Available

Drug created at May 20, 2019 14:53 / Updated at June 12, 2020 16:53