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Displaying results 791 - 800 of 2828 in total
  1. Drug

    Lipegfilgrastim

    go.drugbank.com/drugs/DB13200
    Approved

    Lipegfilgrastim, previously known as XM22, is a pegylated, recombinant granulocyte colony-stimulating factor (G-CSF) that was synthetized using a highly site-specific glycoPEGylation technology . It is used as an alternate to DB00019 for...

  2. Drug

    Clindamycin

    go.drugbank.com/drugs/DB01190
    ApprovedInvestigationalVet approved

    Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris.

    Mixtures: CLINZOL-FEMCategories: Genito Urinary System and Sex Hormones
  3. Target

    Solute carrier family 22 member 4

    go.drugbank.com/bio_entities/BE0000757
    TargetTransporterHumans

    Also mediates the bidirectional transport of acetycholine, although the exact transport mechanism has not been fully identified yet (PubMed:22206629). … Transports one sodium ion with one ergothioeine molecule (By similarity).

    Synonyms: ET transporter, Ergothioneine transporterFunction: acetylcholine transmembrane transporter activity
  4. Target

    Ephrin type-A receptor 4

    go.drugbank.com/bio_entities/BE0009438
    TargetHumans

    During development of the cochlear organ of Corti, regulates pillar cell separation by forming a ternary complex with ADAM10 and CADH1 which facilitates the cleavage of CADH1 by ADAM10 and disruption of

    Synonyms: SEK, Tyrosine-protein kinase receptor SEK
  5. Drug

    Reserpine

    go.drugbank.com/drugs/DB00206
    ApprovedWithdrawn

    An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon termin...

    Mixtures: Ser-Ap-Es, Ser-AP-ES TabCategories: Membrane Transport Modulators
  6. Drug

    Insulin lispro

    go.drugbank.com/drugs/DB00046
    ApprovedInvestigational

    These biochemical changes result in a reduced tendency for self-association resulting in dissolution to a dimer and then to a monomer that is absorbed more rapidly after subcutaneous injection compared

  7. Drug

    Tuaminoheptane

    go.drugbank.com/drugs/DB13238
    Experimental

    Tuaminoheptane is a sympathomimetic drug typically used as a nasal decongestant.

  8. Drug

    Sunitinib

    go.drugbank.com/drugs/DB01268
    ApprovedInvestigational

    Sunitinib is a small-molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor. On January 26, 2006, the agent was formally approved by the US FDA for the indications of treating renal cell carcinoma (RCC) and imatinib-resistant g...

  9. Drug

    Edoxaban

    go.drugbank.com/drugs/DB09075
    ApprovedInvestigational

    It is indicated to reduce the risk of stroke and systemic embolism (SE) in patients with nonvalvular atrial fibrillation (NVAF) and for the treatment of deep vein thrombosis (DVT) and pulmonary embolism

  10. Drug

    Fosnetupitant

    go.drugbank.com/drugs/DB14019
    ApprovedInvestigational

    Generally, 25% to 30% of patients with a diagnosis of cancer receive chemotherapy as a treatment modality and 70% to 80% of these patients undergoing chemotherapy treatment may experience nausea and vomiting