Solute carrier family 22 member 4

BE0000757ProteinHumansSLC22A4

Transporter that mediates the transport of endogenous and microbial zwitterions and organic cations (PubMed:10215651, PubMed:15107849, PubMed:15795384, PubMed:16729965, PubMed:20601551, PubMed:22206629, PubMed:22569296, PubMed:29530864). It is acted on by 38 drugs in DrugBank.

Gene name
SLC22A4
UniProtKB entry
Q9H015Swiss-Prot
Cellular location
Apical cell membrane
Residues / weight
551 residues · 62,154 Da
Also known as
Ergothioneine transporter · ET transporter · ETT · ETTh · OCTN1

Resolves to

Protein
UniProtQ9H015UniProt nameS22A4_HUMAN
Gene
HGNCHGNC:10968NCBI Gene6583GenBank2605501GeneCardsSLC22A4
Pharmacology
KEGGhsa:6583
Drugs

What you can answer from here — as of September 07, 2019

38DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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18GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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72+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Solute carrier family 22 member 4, how selective are they, and which programs against it are still in active trials?

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