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Hypoxanthine
go.drugbank.com/drugs/DB04076InvestigationalHypoxanthine is a purine and a reaction intermediate in the metabolism of adenosine and in the formation of nucleic acids by the salvage pathway.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesTaurocholic acid
go.drugbank.com/drugs/DB04348ApprovedThe product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagog...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesAldosterone
go.drugbank.com/drugs/DB04630InvestigationalA hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.
Categories: P-glycoprotein inducers, P-glycoprotein substratesCoumarin
go.drugbank.com/drugs/DB04665InvestigationalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesZomepirac
go.drugbank.com/drugs/DB04828ApprovedWithdrawnZomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid reactions. The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesNebivolol
go.drugbank.com/drugs/DB04861ApprovedInvestigationalNebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and di...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates1,2-Benzodiazepine
go.drugbank.com/drugs/DB12537ApprovedInvestigationalWithdrawnBenzodiazepine is under investigation for the prevention of Delirium and C.Surgical Procedure; Cardiac. Benzodiazepine has been investigated for the treatment of Obesity, Sleep Apnea, Obstructive, and Disorders of Gallbladder, Biliary Tr...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesPiperine
go.drugbank.com/drugs/DB12582InvestigationalBioperine has been used in trials studying the treatment of Multiple Myeloma and Deglutition Disorders.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsRitanserin
go.drugbank.com/drugs/DB12693InvestigationalRitanserin has been used in trials studying the treatment of Cocaine-Related Disorders.
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme Inhibitors