Piperine

DB12582InvestigationalSmall molecule

Bioperine has been used in trials studying the treatment of Multiple Myeloma and Deglutition Disorders.

Mechanism: Pharmacologically active on Sterol O-acyltransferase 1, Transient receptor potential cation channel subfamily V member 1, and Transient receptor potential cation channel subfamily A member 1
Curator reviewed
Formula / weight: C₁₇H₁₉NO₃ · 285.3377 g/mol (avg)
Also known as: Bioperine
Code names: FEMA NO. 2909

Resolves to

Compound

UNIIU71XL721QKCAS94-62-2ChEMBLCHEMBL43185ChEBI28821PubChem638024KEGGC03882

Clinical / RWD

RxNorm1311146

Structure

InChIKeyMXXWOMGUGJBKIW-YPCIICBESA-NSMILESO=C(\C=C\C=C\C1=CC2=C(OCO2)C=C1)N1CCCCC1

Targets

P35610SOAT1Q8NER1TRPV1O75762TRPA1P27338MAOBO14649KCNK3Q9NPC2KCNK9Q7Z418KCNK18P21397MAOA+1 more

Transporters

Q9Y6L6SLCO1B1P08183ABCB1Q9UNQ0ABCG2O15245SLC22A1O75751SLC22A3

What you can answer from here — as of September 15, 2026

10Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

5TransportersSubstrate / inhibitor direction, not just membership

Listed above

334Drug interactionsStructured to mechanism, not free text

11Clinical trialsPhase, status and sponsor resolved per trial

2Marketed productsAcross 1 country and 2 labellers

22+ReferencesStructured and connected to the statements they support

Which drugs share a target with Piperine, and which of those have an active Phase 3 trial?

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