Search

Displaying results 8041 - 8050 of 10000 in total
  1. Drug

    GTB-3550

    go.drugbank.com/drugs/DB18494
    Investigational

    GTB-3550 is a single-chain, tri-specific scFv recombinant fusion protein conjugate composed of the variable regions of the heavy and light chains of anti-CD16 and anti-CD33 antibodies and a modified form

    Synonyms: single chain recombinant trispecific killer engager consistent of anti-CD16 scFV spliced to anti-CD33 scFV with a modified IL-15 linker
  2. Drug

    SB-269970

    go.drugbank.com/drugs/DB13988
    Experimental

    In the studies performed with this agent, it has been suggested that SB-269970 acts either as a selective antagonist or inverse agonist of the serotonin receptor 7 (5-HT7).[A31816,A31817]

  3. Drug

    Prostaglandin D2

    go.drugbank.com/drugs/DB02056
    Experimental

    Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects. … The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages.

  4. Drug

    CL-315555

    go.drugbank.com/drugs/DB18757
    Experimental

    CL-315555 is the C isomer of [Verteporfin].

  5. Drug

    Medetomidine

    go.drugbank.com/drugs/DB11428
    ExperimentalVet approved

    The marketed product is a racemic mixture of two stereoisomers from which dexmedetomidine is the main active isomer. … The drug has been developed by Orion Pharma. In the United States, it is currently approved for its veterinary use in dogs and distributed by Pfizer Animal Health.

    Categories: Adrenergic alpha-2 Receptor Agonists
  6. Drug

    Marbofloxacin

    go.drugbank.com/drugs/DB11426
    ExperimentalVet approved

    A formulation of marbofloxacin combined with clotrimazole and dexamethasone is available under the name Aurizon. … Marbofloxacin is a carboxylic acid, part of the third generation of antibiotic fluoroquinolones. It is used in veterinary medicine.

  7. Drug

    Ultevursen

    go.drugbank.com/drugs/DB17835
    Investigational

    It was developed by ProQR Therapeutics and is being investigated for the treatment of retinitis pigmentosa. … Ultevursen is a single-stranded RNA-based oligonucleotide targeting exon 13 of the USH2A gene that encodes usherin.

  8. Drug

    Choline alfoscerate

    go.drugbank.com/drugs/DB04660
    Investigational

    (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules. [PubChem] … A component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids.

    Synonyms: Glicerofosfato de colina, Glycerophosphate de choline
  9. Drug

    Proscillaridin

    go.drugbank.com/drugs/DB13307
    Experimental

    Studies suggest the potential cytotoxic and anticancer property of proscillaridin, based on evidence of the drug potently disrupting topoisomerase I and II activity at nanomolar drug concentrations [A27193 … Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima).

  10. Drug

    Ruserontinib

    go.drugbank.com/drugs/DB21555
    Investigational

    The usage of the INN stem '-tinib' in the name indicates that Ruserontinib is a tyrosine kinase inhibitor.