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Naftopidil
go.drugbank.com/drugs/DB12092InvestigationalNaftopidil has been investigated for the treatment of Disorder of Urinary Stent.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesVinpocetine
go.drugbank.com/drugs/DB12131InvestigationalVinpocetine has been investigated for the treatment of Epilepsy.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesBMS-275183
go.drugbank.com/drugs/DB12144InvestigationalBMS-275183 has been used in trials studying the treatment of Tumors and Non-small Cell Lung Cancer.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesLandiolol
go.drugbank.com/drugs/DB12212ApprovedInvestigationalLandiolol is a rapid-acting beta (β)-1 adrenergic receptor blocker that blocks the positive chronotropic effect of the beta-1 selective agonist norepinephrine. It works to reduce the heart rate, myocardial contractility, and conduction v...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsMK-0777
go.drugbank.com/drugs/DB12238InvestigationalMK-0777 has been used in trials studying the treatment of Schizophrenia, Anxiety Disorder, and Generalized Anxiety Disorder.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesBenzbromarone
go.drugbank.com/drugs/DB12319ApprovedWithdrawnBenzbromarone has been used in trials studying the basic science and treatment of Heart Failure, Hyperuricemia, Chronic Kidney Disease, Abnormal Renal Function, and Gout and Asymptomatic Hyperuricemia.
Categories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsIndirubin
go.drugbank.com/drugs/DB12379InvestigationalIndirubin is under investigation in clinical trial NCT01735864 (Dosage Determination Trial for Indigo Naturalis Extract in Oil Ointment).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesLisofylline
go.drugbank.com/drugs/DB12406InvestigationalLisofylline has been investigated for the treatment of Type 1 Diabetes Mellitus.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesOmadacycline
go.drugbank.com/drugs/DB12455ApprovedInvestigationalOmadacycline has been used in trials studying the treatment of Bacterial Pneumonia, Bacterial Infections, Community-Acquired Infections, and Skin Structures and Soft Tissue Infections. Omadacycline represents a significant advance over t...
Categories: P-glycoprotein substratesLucinactant
go.drugbank.com/drugs/DB04897ApprovedIt contains sinapultide, a novel, hydrophobic, 21-amino acid peptide (leucine and lysine repeating units, KL4 peptide) designed to mimic human surfactant protein-B (SB-P).