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Displaying results 8071 - 8080 of 10000 in total
  1. Drug

    SHR-4595

    go.drugbank.com/drugs/DB33992
    Experimental

    SHR-4595 is under investigation in clinical trial NCT07830199 (A Clinical Study of SHR-4595 Injection in Patients With Advanced Solid Tumors to Evaluate Safety, Tolerability and Pharmacokinetics).

  2. Drug

    Zilovertamab vedotin

    go.drugbank.com/drugs/DB18457
    Investigational

    mc-vc-PAB), and a monomethyl auristatin E (MMAE) cytotoxin. … Zilovertamab vedotin is an Antibody-drug conjugate (ADC) comprising an anti-ROR1 monoclonal antibody (UC-961), a proteolytically cleavable maleimidocaproyl-valine-citrulline-para-aminobenzoate linker (

  3. Drug

    Pilavapadin

    go.drugbank.com/drugs/DB21552
    Investigational

    Pilavapadin is under investigation in clinical trial NCT06203002 (A Dose-ranging Study in Patients With Diabetic Peripheral Neuropathic Pain (DPNP)).

  4. Drug

    Fulzerasib

    go.drugbank.com/drugs/DB21609
    Investigational

    Fulzerasib is under investigation in clinical trial NCT06936644 (A Multicenter, Single-arm Phase II Study to Evaluate the Efficacy and Safety of Fulzerasib (IBI351) in Combination With Ivonescimab (AK- … The usage of the INN stem '-rasib' in the name indicates that Fulzerasib is a Ras protein inhibitor.

  5. Drug

    Tengonermin

    go.drugbank.com/drugs/DB16689
    Investigational

    [A233270] A study also demonstrated that binding of the NGR-motif to CD13 determined both the homing of NGR-hTNF to tumor vessels and the increase in its antiangiogenic activity.[A233270]

  6. Drug

    Cathinone

    go.drugbank.com/drugs/DB01560
    ExperimentalIllicit

    Cathinone was added to the Controlled Substances Act's Schedule I in 1993 in compliance with international laws. … Cathinone is a monoamine alkaloid found in the shrub Catha edulis (Khat).

  7. Drug

    5-methoxy-N,N-dimethyltryptamine

    go.drugbank.com/drugs/DB14010
    IllicitInvestigational

    5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. … This drug, as well as [dimethyltryptamine] and [bufotenin], have been registered to be used in South America in religious and spiritual rituals.

    Categories: N,N-DimethyltryptamineSynonyms: 5-methoxy-N,N-dimethyltryptamine, N,N-dimethyl-5-methoxytryptamine
  8. Drug

    BBIBP-CorV

    go.drugbank.com/drugs/DB15807
    Investigational

    Investigation shows this vaccine induces neutralizing antibodies in several mammalian species while also showing protective efficacy with SARS-CoV-2 challenge in rhesus macaques[A219763]. … As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials.

  9. Drug

    Zeteletinib

    go.drugbank.com/drugs/DB21491
    Investigational

    Zeteletinib is under investigation in clinical trial NCT03780517 (Safety, Efficacy, and Tolerability of BOS172738 in Patients With Advanced Rearranged During Transfection (RET) Gene-Altered Tumors). … The usage of the INN stem '-tinib' in the name indicates that Zeteletinib is a tyrosine kinase inhibitor.

  10. Drug

    Xeruborbactam

    go.drugbank.com/drugs/DB21512
    Investigational

    Xeruborbactam is under investigation in clinical trial NCT07104162 (A Study to Investigate Safety and Pharmacokinetics of Intravenous Cefiderocol/Xeruborbactam in Participants With Renal Impairment). … The usage of the INN stem '-bactam' in the name indicates that Xeruborbactam is a ẞ-lactamase inhibitor.