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Displaying results 8081 - 8090 of 10000 in total
  1. Drug

    Tipapkinogene sovacivec

    go.drugbank.com/drugs/DB06239
    Investigational

  2. Drug

    GB-13

    go.drugbank.com/drugs/DB18387
    Experimental

    GB-13 is a genetically engineered recombinant protein consisting of an IL13Ra2-targeted genetically engineered mutant of IL-13 and PE4E, a derivative of Pseudomonas exotoxin A.

  3. Drug

    Crefmirlimab

    go.drugbank.com/drugs/DB17577
    Investigational

    Crefmirlimab is an anti-human CD8 probe targeting the CD8 antigen, for the diagnosis of various cancers.

    Synonyms: Iab22m2c (antibody fragment against the human cd8-antigen on cd8-positive t-cells)
  4. Drug

    PYX-201

    go.drugbank.com/drugs/DB18382
    Investigational

    PYX-201 is an antibody-drug conjugate directed against the extra domain-B splice variant of fibronectin.

  5. Drug

    D-Phenylalanine

    go.drugbank.com/drugs/DB02556
    Experimental

    An essential aromatic amino acid that is a precursor of melanin; dopamine; noradrenalin (norepinephrine), and thyroxine. [PubChem]

    Synonyms: D-Phenylalanine
  6. Drug

    Ertiprotafib

    go.drugbank.com/drugs/DB06521
    Experimental

    Ertiprotafib belongs to a novel class of insulin sensitizers developed for treatment of type 2 diabetes. … In insulin-resistant rodent models, ertiprotafib and a close analog lowered both fasting blood glucose and insulin levels and improved glycemic excursion during an oral glucose tolerance test.

  7. Drug

    Veru-111

    go.drugbank.com/drugs/DB16462
    Investigational

    VERU-111, an investigational drug intended for various therapeutic uses, was under investigation in clinical trials NCT04842747, NCT03752099, NCT04388826, NCT04844749, NCT05008510, and NCT05079360. … These trials aimed to evaluate its efficacy, safety, and tolerability in conditions such as SARS-CoV-2 infection, metastatic castration-resistant prostate cancer (mCRPC), respiratory distress syndrome

  8. Drug

    Colchiceine

    go.drugbank.com/drugs/DB15534
    Approved

    Colchiceine is one of several metabolites of the anti-gout medication [colchicine].[A192714]

    Synonyms: O-Demethylcolchicine, 10-O-demethylcolchicine
  9. Drug

    1D-myo-inositol 1,4,5-trisphosphate

    go.drugbank.com/drugs/DB03401
    Experimental

    These calcium ions stimulate the activity of B kinase or calmodulin. … Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane.

    Synonyms: D-myo-Inositol 1,4,5-trisphosphate, D-myo-Inositol-1,4,5-triphosphate
  10. Drug

    NPI 32101

    go.drugbank.com/drugs/DB05264
    Experimental

    This combination of pharmacological properties may have additional therapeutic uses beyond dermatology.