Colchiceine

DB15534ApprovedSmall molecule

Colchiceine is one of several metabolites of the anti-gout medication colchicine.

Chemical structure of Colchiceine
Formula / weight
C21H23NO6 · 385.416 g/mol (avg)
First approval
United States, 2020
Also known as
10-O-demethylcolchicine

Resolves to

Compound
UNIIHJ30158L57CAS477-27-0ChEMBLCHEMBL323668
Clinical / RWD
RxNorm2174385
Structure
InChIKeyPRGILOMAMBLWNG-UHFFFAOYSA-NSMILESCOC1=C(OC)C(OC)=C2C(CCC(NC(C)=O)C3=CC(=O)C(O)=CC=C23)=C1
Targets
O60885BRD4P07437TUBBQ71U36TUBA1A

What you can answer from here — as of April 02, 2025

3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
4Marketed productsAcross 1 country and 4 labellers
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7+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Colchiceine, and which of those have an active Phase 3 trial?

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