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Displaying results 8091 - 8100 of 10000 in total
  1. Drug

    Elacytarabine

    go.drugbank.com/drugs/DB05494
    Investigational

    Elacytarabine is a fatty acid derivative of [cytarabine], an approved cytotoxic cancer drug. Cytarabine has limitations such as minimal uptake in solid tumours and is only used to treat leukaemia. … Elacytarabine is a patented new chemical entity of the nucleoside analog class, with improved biological properties and the potential to treat solid tumours such as non-small cell lung cancer, malignant

  2. Drug

    Squalene

    go.drugbank.com/drugs/DB11460
    ApprovedInvestigationalVet approvedWithdrawn

    It is a natural 30-carbon isoprenoid compound and intermediate metabolite in the synthesis of cholesterol. It is not susceptible to lipid peroxidation and provides skin protection. … It is ubiquitously distributed in human tissues where it is transported in serum generally in association with very low density lipoproteins. Squalene is investigated as an adjunctive cancer therapy.

  3. Drug

    Dacetuzumab

    go.drugbank.com/drugs/DB12589
    Investigational

    Dacetuzumab has been used in trials studying the treatment of Multiple Myeloma, Non-Hodgkin Lymphoma, Leukemia, Lymphocytic, Chronic, and Lymphoma, Large B-Cell, Diffuse. … It is a humanized anti-CD40 antibody and induces cytotoxicity in human multiple myeloma cells.

  4. Drug

    GI-4000

    go.drugbank.com/drugs/DB05698
    Investigational

    A vaccine containing a heat-killed recombinant <em>Saccharomyces cerevisiae</em> yeast transfected with mutated forms of Ras, an oncogene frequently found in solid tumors, with potential immunostimulant

  5. Drug

    Astaxanthin

    go.drugbank.com/drugs/DB06543
    Investigational

    It may be found in fish feed or some animal food as a color additive. … Astaxanthin is a keto-carotenoid in the terpenes class of chemical compounds. It is classified as a xanthophyll but it is a carotenoid with no vitamin A activity.

  6. Drug

    Corticorelin

    go.drugbank.com/drugs/DB05394
    Investigational

    Corticotropin-releasing factor is studied in the treatment of brain cancer. It is made naturally by the hypothalamus (a part of the brain) and can also be made in the laboratory. … Human corticotropin-releasing factor may help reduce symptoms caused by edema (swelling) of the brain. It is a type of neurohormone, also called hCRF.

  7. Drug

    Pexelizumab

    go.drugbank.com/drugs/DB04949
    Investigational

    Pexelizumab is a humanized monoclonal antibody used as an immunosuppressive drug. It is being investigated by Alexion Pharmaceuticals.

  8. Drug

    Protirelin

    go.drugbank.com/drugs/DB09421
    Approved

    Although not currently available in any FDA-approved product, protirelin is a component of the TRH Test where it is used to test the response of the anterior pituitary gland in conditions such as secondary … Protirelin is the pharmaceutically available synthetic analogue of the endogenous peptide thyrotropin-releasing hormone (TRH).

  9. Drug

    Daleuton

    go.drugbank.com/drugs/DB00154
    InvestigationalNutraceutical

    A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. It differs from arachidonic acid, 5,8,11,14-eicosatetraenoic acid, only at position 5.

    Synonyms: 20:3, n-6,9,12 all-cis, C20:3, n-6,9,12 all-cis
  10. Drug

    Benzimate

    go.drugbank.com/drugs/DB05170
    Experimental

    It is currently under investigation by AmpliMed and is in phase I of clinical trial. … Benzimate is the lead compound selected from a series of compounds known as benzimidazoles.