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Displaying results 8141 - 8150 of 9117 in total
  1. Drug

    Bacillus calmette-guerin substrain russian BCG-I live antigen

    go.drugbank.com/drugs/DB16648
    ApprovedInvestigational

    thought to work by stimulating a local immune and inflammatory response in the bladder. … [L32729,A232264] The live Russian BCG-I substrain of BCG was granted a notice of compliance with conditions by Health Canada in February 2021.

  2. Drug

    Mibavademab

    go.drugbank.com/drugs/DB16673
    Investigational

    Mibavademab is under investigation in clinical trial NCT04159415 (Study of REGN4461, a Leptin Receptor Agonist Antibody, in Patients With Generalized Lipodystrophy).

  3. Drug

    Nadecnemab

    go.drugbank.com/drugs/DB16677
    Investigational

    Nadecnemab is under investigation in clinical trial NCT03956550 (A Study to Examine the Efficacy and Safety of REGN5069 in Patients With Pain Due to Osteoarthritis of the Knee).

  4. Drug

    Odronextamab

    go.drugbank.com/drugs/DB16684
    ApprovedInvestigational

    [L43887,L43892] A phase I clinical study (NCT02290951) showed that in heavily pre-treated patients with B-cell non-Hodgkin lymphoma, odronextamab elicited a durable response with a manageable safety … Odronextamab is a hinge-stabilized, fully human immunoglobulin G4 (IgG4)-based CD20×CD3 bispecific antibody currently evaluated for the treatment of relapsed/refractory (R/R) B-Cell non-Hodgkin lymphoma

  5. Drug

    Streptococcus pneumoniae type 12F capsular polysaccharide diphtheria CRM197 protein conjugate antigen

    go.drugbank.com/drugs/DB16716
    ApprovedInvestigational

    * serotype 12F individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of *Corynebacterium diphtheriae* strain C7 (β197). … Streptococcus pneumoniae type 12F capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae

  6. Drug

    Methyl 2,5-dihydroxycinnamate

    go.drugbank.com/drugs/DB16769
    Experimental

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    Cepharanthine

    go.drugbank.com/drugs/DB16824
    Investigational

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Chlorocresol

    go.drugbank.com/drugs/DB16864
    Investigational

    Synonyms: p-Chloro-m-cresolCategories: Compounds used in a research, industrial, or household setting
  9. Drug

    SRP-6004

    go.drugbank.com/drugs/DB16998
    Investigational

    A recombinant AAVrh74 gene therapy expressing the dysferlin transgene under control of a muscle-specific promoter (rAAVrh74.MHCK7.DYSF.DV).

  10. Drug

    MRK-003

    go.drugbank.com/drugs/DB17015
    Experimental

    MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. It is the preclinical analog of [MK-0752], a drug in clinical development.[A252682]