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Avoralstat
go.drugbank.com/drugs/DB12120InvestigationalAvoralstat has been used in trials studying the prevention of HAE and Hereditary Angioedema.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 3-(2-((4-Carbamimidoylphenyl)carbamoyl)-4-ethenyl-5-methoxyphenyl)-6-((cyclopropylmethyl)carbamoyl)pyridine-2-carboxylic acid, 3-[2-(4-carbamimidoyl-phenylcarbamoyl)-5-methoxy-4-vinyl-phenyl]-6-(cyclopropylmethyl-carbamoyl)-pyridine-2-carboxylic acidBalicatib
go.drugbank.com/drugs/DB12239InvestigationalBalicatib has been used in trials studying the treatment of Osteoporosis and Knee Osteoarthritis.
Categories: Heterocyclic Compounds, 1-RingCarmegliptin
go.drugbank.com/drugs/DB12268InvestigationalCarmegliptin has been used in trials studying the treatment of Diabetes Mellitus Type 2.
Categories: Dipeptidyl Peptidase 4, Heterocyclic Compounds, 2-RingMuscimol
go.drugbank.com/drugs/DB12458InvestigationalMuscimol has been used in trials studying the treatment of Epilepsy and Parkinson's Disease.
Categories: GABA-A Receptor Agonists, Heterocyclic Compounds, 1-RingSynonyms: 5-(aminomethyl)-3(2H)-isoxazoloneAcotiamide
go.drugbank.com/drugs/DB12482InvestigationalAcotiamide has been used in trials studying the treatment of Dyspepsia and Functional Dyspepsia.
Categories: Heterocyclic Compounds, 1-RingLetrazuril
go.drugbank.com/drugs/DB12663InvestigationalLetrazuril has been used in trials studying the treatment of HIV Infections and Cryptosporidiosis.
Categories: Heterocyclic Compounds, 1-RingFarampator
go.drugbank.com/drugs/DB15012InvestigationalFarampator is under investigation in clinical trial NCT00113022 (Org 24448 to Treat Major Depression).
Categories: Heterocyclic Compounds, 1-RingMito-4509
go.drugbank.com/drugs/DB05846ExperimentalIt is used to treat Parkinson's Disease, Alzheimer's Disease, Retinal Disorders and other neurologic Disorders. … Mito-4509 is a non-feminizing estrogen analog that could affect mitochondrial metabolic pathways.
Daledalin
go.drugbank.com/drugs/DB09189ExperimentalDaledin (UK-3557-15) is a selective norepinephrine reuptake inhibitor. It has no effects on the reuptake of serotonin or dopamine, and no antihistamine or anticholinergic properties. … It was in trials for depression in the 1970s but never marketed.
Categories: Heterocyclic Compounds, 2-RingOpaganib
go.drugbank.com/drugs/DB12764Investigational[L27436] This drug has potential anticancer, anti-inflammatory, and antiviral activities, with potential applications in oncology, inflammation, the gastrointestinal system, and COVID-19. … Opaganib, also known as ABC294640, is a selective [sphingosine kinase-2 (SK2)](https://go.drugbank.com/polypeptides/Q9NRA0) inhibitor that is orally administered.
Synonyms: 4-Pyridinylmethyl 3(4-Chlorophenyl)Adamantine Carboxamide, 4-Pyridinylmethyl-3-(4-Chlorophenyl) Adamantine CarboxamideCategories: Heterocyclic Compounds, 1-Ring