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MGC030
go.drugbank.com/drugs/DB33973ExperimentalMGC030 is a biologic drug. MGC030 is under investigation in clinical trial NCT07822399 (A Study of MGC030 in Participants With Advanced Solid Tumors).
VH5356136
go.drugbank.com/drugs/DB33975ExperimentalVH5356136 is a small molecule drug. … VH5356136 is under investigation in clinical trial NCT07822477 (A Study to Investigate Safety, Tolerability and Pharmacokinetics of VH5356136 in Adult Participants Without HIV).
MWN117
go.drugbank.com/drugs/DB33969ExperimentalMWN117 is a small molecule drug. MWN117 is under investigation in clinical trial NCT07824804 (Phase 1 Clinical Study of MWN117 Injection in Healthy Participants and Participants With Obesity).
CM583
go.drugbank.com/drugs/DB33976ExperimentalCM583 is a small molecule drug. CM583 is under investigation in clinical trial NCT07823764 (Study of CM583 in Healthy Participants).
Pentobarbital
go.drugbank.com/drugs/DB00312ApprovedVet approvedA short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 InducersSynonyms: 5-Ethyl-5-(1-methyl-butyl)-pyrimidine-2,4,6-trione, 5-ethyl-5-(1-methylbutyl)barbituric acidCalcium glucoheptonate
go.drugbank.com/drugs/DB00326ApprovedInvestigationalCalcium supplements such as calcium gluceptate are taken by individuals who are unable to get enough calcium in their regular diet or who have a need for more calcium.
Synonyms: Calcium glucoheptonate (1:2), calcium bis[(2ξ)-D-glycero-D-gulo-heptonate]Products: Sirop De Calcium 625mg/5mlMethadone
go.drugbank.com/drugs/DB00333ApprovedInvestigationalMethadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. … (due to a lack of active metabolites), minimal accumulation in renal failure, good bioavailability, low cost, and a long duration of action.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: 6-Dimethylamino-4,4-diphenyl-3-heptanoneProtriptyline
go.drugbank.com/drugs/DB00344ApprovedSee toxicity section below for a complete listing of side effects. Protriptyline may be used for the treatment of depression. … Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines.
Categories: P-glycoprotein inhibitorsSynonyms: 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine, 5-(3-methylaminopropyl)-5H-dibenzo[a,d]cyclohepteneTrimethadione
go.drugbank.com/drugs/DB00347ApprovedWithdrawnAn anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring