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Lorcaserin
go.drugbank.com/drugs/DB04871ApprovedInvestigationalWithdrawnThis decision was based on the results of a clinical trial assessing the risk of heart-related problems that found that patients treated with lorcaserin may have a higher risk of cancer. … Lorcaserin is marketed as a salt form called Belviq, which is lorcaserin hydrochloride.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingOlaratumab
go.drugbank.com/drugs/DB06043ApprovedInvestigationalOlaratumab (IMC-3G3) is a fully human IgG1 monoclonal antibody with antitumor activity that selectively binds the external domain of human platelet-derived growth factor receptor (PDGFR)-α with high affinity … It is composed of two heavy chain molecule fragments and 2 light chain fragments.
Nylidrin
go.drugbank.com/drugs/DB06152ApprovedWithdrawnNylidrin is a peripheral vasodilator.
Categories: 2-Amino-1-Phenylethanol Derivatives, Cytochrome P-450 SubstratesSuvorexant
go.drugbank.com/drugs/DB09034ApprovedInvestigationalSuvorexant is a selective dual antagonist of orexin receptors OX1R and OX2R that promotes sleep by reducing wakefulness and arousal. It has been approved for the treatment of insomnia.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: BELSOMRA® 15 MG, BELSOMRA® 10 MGCefminox
go.drugbank.com/drugs/DB09062ExperimentalCefminox (INN) is a second generation cephalosporin antibiotic. It is approved for use in Japan.
Categories: Heterocyclic Compounds, 2-RingDaclatasvir
go.drugbank.com/drugs/DB09102ApprovedInvestigationalWithdrawnDaclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment of chronic HCV genotype 1 and 3 infection. … 3 patients.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: I-HEP CLASTAVIR 30, I-HEP CLASTAVIR 60Ubidecarenone
go.drugbank.com/drugs/DB09270ApprovedInvestigationalNutraceutical[A7874] It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation. … [L1062] Ubidecarenone is sold as a dietary supplement and is not FDA approved as a drug - it is not meant to treat, cure or prevent any disease.
Synonyms: Co-enzyme Q 10, Coenzyme Q 10Mixtures: Kordel"s CoQ10 75MG + Omega 3-6 Capsules, Q 10 Suprabio +L-CarnitinePolycarbophil
go.drugbank.com/drugs/DB09311ApprovedWithdrawnPolycarbophil calcium is a synthetic polymer manufactured from the cross-linking of polyacrylic acid with divinyl glycol and a calcium counter-ion. … Polycarbophil calcium is a stool stabilizer used to treat constipation. This drug may also be used to help relieve the symptoms of irritable bowel syndrome or diarrhea.
Categories: Compounds used in a research, industrial, or household settingOctasulfur
go.drugbank.com/drugs/DB09353ApprovedSulfur is a chemical element that is present in all living tissues. The most commonly used form of pharmaceutical sulfur is Octasulfur (S8).
Mixtures: NW SULPHUR 2%W/W AND SALICYLIC ACID 2%W/W CREAM, SulfaCleanse 8/4Products: Acne All-Star 3-in-1 Acne Cleanser, Mask and Spot Treatment, X Out Spot CorrectorEsterified estrogens
go.drugbank.com/drugs/DB09381ApprovedEsterified estrogens contain a mixture of estrogenic substances; the principle component is estrone. … Preparations contain 75% to 85% sodium estrone sulfate and 6% to 15% sodium equilin sulfate such that the total is not <90%.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates