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Emivirine
go.drugbank.com/drugs/DB08188InvestigationalEmivirine has been used in trials studying the treatment of HIV Infections.
Ad5-nCoV
go.drugbank.com/drugs/DB15655Investigational[L12675,L12678] It is being developed by CanSino Biologics Inc., in partnership with the Beijing Institute of Biotechnology, who in March 2020 announced the approval of a phase I clinical trial (ChiCTR2000030906 … The study will evaluate antibody response in healthy patients between the ages of 18 and 60 who will receive one of three study doses, with follow-up taking place at weeks 2 and 4 and months 3 and 6 post-vaccination
COVID-19 convalescent plasma
go.drugbank.com/drugs/DB15692Investigational[L14333] Although there are no formal clinical trial results for the safety or efficacy of COVID-19 convalescent plasma, early results from 5000 patients under the FDA expanded access program suggest … COVID-19 convalescent plasma is plasma collected from patients who have acquired and subsequently recovered from COVID-19 and which contains antibodies against the causative agent SARS-CoV-2.
Mito-4509
go.drugbank.com/drugs/DB05846ExperimentalIt is used to treat Parkinson's Disease, Alzheimer's Disease, Retinal Disorders and other neurologic Disorders.
Dendritic cells vaccine
go.drugbank.com/drugs/DB15803InvestigationalWith a better safety profile than inactivated and live-attenuated virus and virus-vector vaccines, the recombinant chimeric DC vaccine reduces the risk of virulence recovery, pre-existing anti-vector immunity … The recombinant chimeric DC vaccine is a subunit-based vaccine candidate investigated for safety and effectiveness against SARS-CoV-2-induced pneumonia.
Dihydroxyacetone
go.drugbank.com/drugs/DB01775ExperimentalIts addition to blood preservation solutions results in better maintenance of 2,3-diphosphoglycerate levels during storage. … It is readily phosphorylated to dihydroxyacetone phosphate by triokinase in erythrocytes. In combination with naphthoquinones it acts as a sunscreening agent. [PubChem]
Tofimilast
go.drugbank.com/drugs/DB11681InvestigationalTofimilast has been used in trials studying the treatment of Asthma and Pulmonary Disease, Chronic Obstructive.
Birinapant
go.drugbank.com/drugs/DB11782InvestigationalBirinapant has been investigated for the treatment of Myelodysplastic Syndrome (MDS) and Chronic Myelomonocytic Leukemia (CMML).
Tofogliflozin
go.drugbank.com/drugs/DB11824InvestigationalTofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type 2.
Lanifibranor
go.drugbank.com/drugs/DB14801InvestigationalLanifibranor is under investigation in clinical trial NCT03008070 (Phase 2b Study in NASH to Assess IVA337).