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Displaying results 8211 - 8220 of 10000 in total
  1. Drug

    Arsthinol

    go.drugbank.com/drugs/DB08928
    Experimental

    Considered well tolerated when compared to other related trivalent organoarsenicals, arsthinol has even undergone recent studies as a potential anticancer agent. … Arsthinol (INN) is an antiprotozoal agent that was first synthesized by Ernst A.H. Friedheim in 1949 via the complexing of acetarsol with 2,3-dimercaptopropanol.

  2. Drug

    Riociguat

    go.drugbank.com/drugs/DB08931
    ApprovedInvestigational

    Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for … Riociguat is marketed under the brand Adempas® by Bayer HealthCare Pharmaceuticals. Treatment with riociguat costs USD $7,500 for 30 days of treatment.

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: Methyl N-[4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methyl-carbaminate
  3. Drug

    Macitentan

    go.drugbank.com/drugs/DB08932
    ApprovedInvestigational

    Macitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH).[L35890] It was first approved by the FDA in 2013. … A combination product (Opsynvi) comprising macitentan and [tadalafil] was approved in Canada in October 2021 for the treatment of PAH.[L39105] It was subsequently approved by the FDA in March 2024.

    Mixtures: OPSYNVI® (MACITENTAN/TADALAFILO) 10MG/40 MG TABLETAS RECUBIERTASCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  4. Drug

    Letosteine

    go.drugbank.com/drugs/DB08939
    Experimental

    Letosteine is a mucolytic used in the treatment of chronic bronchopneumopathies and related conditions.

  5. Drug

    Kebuzone

    go.drugbank.com/drugs/DB08940
    Investigational

    Kebuzone (also known as ketophenylbutazone ) is a non-steroidal anti-inflammatory drug.

    Mixtures: Rheumesser 3 ml - AmpullenCategories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-Ring
  6. Drug

    Indoprofen

    go.drugbank.com/drugs/DB08951
    ApprovedWithdrawn

    A drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.

    Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 2-Ring
  7. Drug

    Ibuproxam

    go.drugbank.com/drugs/DB08955
    ApprovedWithdrawn

    Ibuproxam is a non steroidal anti-inflammatory drug (NSAID).

    Categories: Non COX-2 selective NSAIDSSynonyms: p-Isobutylhydratropohydroxamic acid
  8. Drug

    Azosemide

    go.drugbank.com/drugs/DB08961
    Investigational

    Azosemide is a loop diuretic used to treat hypertension, edema, and ascites.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 2-chloro-5-(1H-tetrazol-5-yl)-N4-2-thenylsulfanilamide, 5-(4'-chloro-5'-sulfamoyl-2'-thenylaminophenyl)tetrazole
  9. Drug

    Glibornuride

    go.drugbank.com/drugs/DB08962
    ApprovedWithdrawn

    Glibornuride is a sulfonylurea-type anti-diabetic drug.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates
  10. Drug

    Glafenine

    go.drugbank.com/drugs/DB08963
    ApprovedWithdrawn

    Glafenine is withdrawn from the American market.