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Displaying results 8221 - 8230 of 10000 in total
  1. Drug

    Faropenem

    go.drugbank.com/drugs/DB12190
    Investigational

    Faropenem has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and Community Acquired Pneumonia.

    Categories: Heterocyclic Compounds, 2-Ring
  2. Drug

    Obatoclax

    go.drugbank.com/drugs/DB12191
    Investigational

    Obatoclax has been used in trials studying the treatment of AML, Leukemia, Myelofibrosis, Hodgkin's Lymphoma, and Mantle-Cell Lymphoma, among others.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  3. Drug

    Terbogrel

    go.drugbank.com/drugs/DB12204
    Investigational

    Terbogrel has been used in trials studying the treatment of Hypertension, Pulmonary.

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Tirasemtiv

    go.drugbank.com/drugs/DB12209
    Investigational

    Tirasemtiv has been used in trials studying the treatment of Myasthenia Gravis, Intermittent Claudication, and Amyotrophic Lateral Sclerosis.

    Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Luseogliflozin

    go.drugbank.com/drugs/DB12214
    Investigational

    Luseogliflozin has been used in trials studying the treatment of Diabetes Melltius, Type 2.

    Categories: Sodium-glucose Cotransporter 2 (SGLT2) InhibitorsProducts: ลูเซฟี 5 มก.
  6. Drug

    Capivasertib

    go.drugbank.com/drugs/DB12218
    ApprovedInvestigational

    Therefore, targeting the PIK3/AKT pathway presents a promising approach for the treatment of breast cancer, leading to the development of capivasertib, a pan-AKT kinase inhibitor. … [A262021] The PIK3/AKT pathway is one of the most commonly activated pathways in breast cancer, mainly through the constitutively active mutation in AKT1, loss of function mutation in PTEN, a negative

    Categories: MATE 1 Inhibitors, MATE 2 Inhibitors
  7. Drug

    Bunazosin

    go.drugbank.com/drugs/DB12230
    Investigational

    Bunazosin has been used in trials studying the treatment of High Blood Pressure.

    Categories: Peripheral alpha-1 blockers, Heterocyclic Compounds, 2-Ring
  8. Drug

    Alpha-galactosylceramide

    go.drugbank.com/drugs/DB12232
    Investigational

    KRN7000 has been used in trials studying the treatment of Lung Cancer, Chronic Hepatitis C, Hepatitis B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and Prevention of GvHD in Patients With

    Synonyms: 1-O-(α-D-galactopyranosyl)-N-hexacosanoylphytosphingosine
  9. Drug

    Bexagliflozin

    go.drugbank.com/drugs/DB12236
    ApprovedInvestigational

    Bexagliflozin is a highly specific and potent sodium-glucose co-transporter 2 (SGLT2) inhibitor. … [A256408,A256413,L44758] Similar to other SGLT2 inhibitors, bexagliflozin contains three basic moieties: glucose, two benzene rings and a methylene bridge.

    Synonyms: D-glucitol, 1,5-anhydro-1-C-(4-chloro-3-((4-(2-(cyclopropyloxy)ethoxy)phenyl)methyl)phenyl)-, (1s)-, (2S,3R,4R,5S,6R)-2-(4-chloro-3-((4-(2-(cyclopropyloxy)ethoxy)phenyl)methyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triolCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  10. Drug

    TAK-733

    go.drugbank.com/drugs/DB12241
    Investigational

    TAK-733 has been used in trials studying the treatment of Advanced Metastatic Melanoma, Advanced Nonhematologic Malignancies, and Advanced Non-hematologic Malignancies.

    Synonyms: (R)-3-(2,3-DIHYDROXYPROPYL)-6-FLUORO-5-(2-FLUORO-4-IODOPHENYLAMINO)-8-METHYLPYRIDO(2,3-D)PYRIMIDINE-4,7(3H,8H)-DIONE, 3-[(2R)-2,3-dihydroxypropyl]-6-fluoro-5-[(2-fluoro-4-iodophenyl)amino]-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dioneCategories: Heterocyclic Compounds, 1-Ring