Tirasemtiv

DB12209InvestigationalSmall molecule

Tirasemtiv has been used in trials studying the treatment of Myasthenia Gravis, Intermittent Claudication, and Amyotrophic Lateral Sclerosis.

Chemical structure of Tirasemtiv
Formula / weight
C12H14N4O · 230.271 g/mol (avg)
Code names
CK-2017357

Resolves to

Compound
UNIIG8WSM7R635CAS1005491-05-3ChEMBLCHEMBL3039529PubChem23729157
Structure
InChIKeyRSQGZEAXODVTOL-UHFFFAOYSA-NSMILESCCC(CC)N1C(=O)NC2=NC=C(N=C12)C#C
Targets
P02585TNNC2

What you can answer from here — as of September 15, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action
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4Clinical trialsPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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Which drugs share a target with Tirasemtiv, and which of those have an active Phase 3 trial?

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