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TAK-243
go.drugbank.com/drugs/DB15013InvestigationalTAK-243 is under investigation in clinical trial NCT03816319 (TAK-243 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Refractory Myelodysplastic Syndrome or Chronic Myelomonocytic
Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingRecombinant CD40-ligand
go.drugbank.com/drugs/DB15015InvestigationalRecombinant CD40-ligand is under investigation in clinical trial NCT00053391 (Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma).
Agatolimod
go.drugbank.com/drugs/DB15018InvestigationalAgatolimod is under investigation in clinical trial NCT00471471 (Vaccine Therapy in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery).
Leriglitazone
go.drugbank.com/drugs/DB15021InvestigationalLeriglitazone is under investigation in clinical trial NCT03917225 (A Clinical Study to Evaluate the Effect of MIN-102 on the Progression of Friedreich's Ataxia in Male and Female Patients).
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2,4-thiazolidinedione, 5-((4-(2-(5-(1-hydroxyethyl)-2-pyridinyl)ethoxy)phenyl)methyl)-, All-ambo-5-((4-(2-(5-(1-hydroxyethyl)pyridin-2-yl)ethoxy)phenyl)methyl)-1,3-thiazole-2,4(3H,5H)-dioneGirentuximab I-124
go.drugbank.com/drugs/DB15025InvestigationalGirentuximab I-124 is under investigation in clinical trial NCT01762592 (REDECT 2: REnal Masses: Pivotal Trial to DEteCT Clear Cell Renal Cell Carcinoma With PET/CT).
Synonyms: Girentuximab I-124, Iodine i 124 girentuximabMK-1064
go.drugbank.com/drugs/DB15028InvestigationalMK-1064 is under investigation in clinical trial NCT02549014 (A Single Dose Study of the Safety, Pharmacokinetics and Pharmacodynamics of MK-1064 (MK-1064-001)).
Daridorexant
go.drugbank.com/drugs/DB15031ApprovedInvestigationalDaridorexant, formerly known as nemorexant, is a selective dual orexin receptor antagonist used to treat insomnia. … It chronically affects the person's daily functioning and long-term health effects, as insomnia is often associated with comorbidities such as hypertension, diabetes, and depression.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesObexelimab
go.drugbank.com/drugs/DB15032InvestigationalObexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).
Flortaucipir
go.drugbank.com/drugs/DB15033InvestigationalFlortaucipir is under investigation in clinical trial NCT03507257 (Longitudinal Early-onset Alzheimer's Disease Study Protocol).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingZanubrutinib
go.drugbank.com/drugs/DB15035ApprovedInvestigational[L10169] It is currently marketed under the trade name BRUKINSA™ and is available as oral capsules. … trial whose tumour is entirely or partially destroyed by a drug.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index