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LAS-190792
go.drugbank.com/drugs/DB33621InvestigationalCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingABT-102
go.drugbank.com/drugs/DB33624InvestigationalCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingTalbutal
go.drugbank.com/drugs/DB00306ApprovedIllicitTalbutal, also called 5-allyl-5-sec-butylbarbituric acid, is a barbiturate with a short to intermediate duration of action. Talbutal is a schedule III drug in the U.S.
Synonyms: 5-allyl-5-sec-butylbarbituric acid, (RS)-5-allyl-5-sec-butylpyrimidine-2,4,6(1H,3H,5H)-trioneCategories: Heterocyclic Compounds, 1-RingChlorthalidone
go.drugbank.com/drugs/DB00310ApprovedInvestigationalThese pathways may play a role in chlorthalidone's cardiovascular risk reduction effects.[A176330] … Chlorthalidone has been shown to have a number of pleiotropic effects that differentiate it from other diuretics such as [DB00999].
Synonyms: 1-keto-3-(3'-sulfamyl-4'-chlorophenyl)-3-hydroxyisoindoline, 1-oxo-3-(3-sulfamyl-4-chlorophenyl)-3-hydroxyisoindolineMixtures: EDARBI CLD®, PRETENOL C 50 TABLETEthoxzolamide
go.drugbank.com/drugs/DB00311ApprovedWithdrawnEthoxzolamide is a sulfonamide used as diuretic and in glaucoma. It inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate.
Synonyms: 6-Ethoxy-1,3-benzothiazole-2-sulfonamideCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingValproic acid
go.drugbank.com/drugs/DB00313ApprovedInvestigational[A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. … a similar degree of anticonvulsive activity.
Synonyms: 2-n-propyl-n-valeric acid, n-DPACategories: Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index