Ethoxzolamide is a sulfonamide used as diuretic and in glaucoma. It inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate. Its pharmacological activity... Its pharmacological activity thus confers the risk for hypokalemia.
- Mechanism
- Curator reviewed
Ethoxzolamide binds to and inhibits carbonic anhydrase I, which plays an essential role in facilitating the transport of CO2 and H+ in the intracellular space, across biological membranes, and in the layers of the extracellular space. Through inhibition of the enzyme, the balance of applicable membrane equilibrium systems are affected.
- Primary indication
- For use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy.Curator reviewed
- Formula / weight
- C9H10N2O3S2 · 258.317 g/mol (avg)
- Also known as
- Ethoxazolamide · Ethoxyzolamide
Resolves to
OUZWUKMCLIBBOG-UHFFFAOYSA-NSMILESCCOC1=CC2=C(C=C1)N=C(S2)S(N)(=O)=OWhat you can answer from here — as of September 13, 2026
Which drugs share a target with Ethoxzolamide, and which of those have an active Phase 3 trial?
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