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Displaying results 8261 - 8270 of 8389 in total

Drug
Vinpocetine
go.drugbank.com/drugs/DB12131
Investigational
Vinpocetine has been investigated for the treatment of Epilepsy.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
Drug
BMS-275183
go.drugbank.com/drugs/DB12144
Investigational
BMS-275183 has been used in trials studying the treatment of Tumors and Non-small Cell Lung Cancer.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
Drug
Landiolol
go.drugbank.com/drugs/DB12212
ApprovedInvestigational
Landiolol is a rapid-acting beta (β)-1 adrenergic receptor blocker that blocks the positive chronotropic effect of the beta-1 selective agonist norepinephrine. It works to reduce the heart rate, myocardial contractility, and conduction v...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Inhibitors
Drug
MK-0777
go.drugbank.com/drugs/DB12238
Investigational
MK-0777 has been used in trials studying the treatment of Schizophrenia, Anxiety Disorder, and Generalized Anxiety Disorder.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
Drug
Benzbromarone
go.drugbank.com/drugs/DB12319
ApprovedWithdrawn
Benzbromarone has been used in trials studying the basic science and treatment of Heart Failure, Hyperuricemia, Chronic Kidney Disease, Abnormal Renal Function, and Gout and Asymptomatic Hyperuricemia.
Categories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 CYP2C9 Inhibitors
Drug
Indirubin
go.drugbank.com/drugs/DB12379
Investigational
Indirubin is under investigation in clinical trial NCT01735864 (Dosage Determination Trial for Indigo Naturalis Extract in Oil Ointment).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 Substrates
Drug
Lisofylline
go.drugbank.com/drugs/DB12406
Investigational
Lisofylline has been investigated for the treatment of Type 1 Diabetes Mellitus.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
Drug
Omadacycline
go.drugbank.com/drugs/DB12455
ApprovedInvestigational
Omadacycline has been used in trials studying the treatment of Bacterial Pneumonia, Bacterial Infections, Community-Acquired Infections, and Skin Structures and Soft Tissue Infections. Omadacycline represents a significant advance over t...
Categories: P-glycoprotein substrates
Drug
Lucinactant
go.drugbank.com/drugs/DB04897
Approved
It contains sinapultide, a novel, hydrophobic, 21-amino acid peptide (leucine and lysine repeating units, KL4 peptide) designed to mimic human surfactant protein-B (SB-P).
Drug
AN0128
go.drugbank.com/drugs/DB05054
Investigational
Of particular importance is P. acnes and its causal role in acne vulgaris. The rise in antibiotic resistance of P. acnes to standard antibiotics necessitates the development of new treatment agents.