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Gadoxetic acid
go.drugbank.com/drugs/DB08884ApprovedInvestigationalGadoxetic acid (gadoxetate) is a paramagnetic gadolinium-containing ionic linear contrast agent in which its salt form, gadoxetate disodium, is used for intravenous injection. … Ethoxybenzyl diethylenetriaminepentaacetic acid is the moiety that chelates with a gadolinium ion and forms a stable complex with it to make up the drug.
Categories: Compounds used in a research, industrial, or household settingProducts: Primovist 0.25 mmol/ml Solution for injection, PRIMOVIST 0.25 MMOL/ML, SOLUTION FOR INJECTIONElosulfase alfa
go.drugbank.com/drugs/DB09051ApprovedInvestigationalElosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. It was approved by the FDA in 2014 for the treatment of Morquio syndrome. … The recommended dose is 2 mg per kg given intravenously over a minimum range of 3.5 to 4.5 hours, based on infusion volume, once every week.
Synonyms: Recombinant human N-acetylgalactosamine-6-sulfatase, Recombinant human N-acetylgalactosamine-6-sulfatase (rhGALNS)Products: Vimizim 1mg/ml Concentrate for Solution for InfusionProtirelin
go.drugbank.com/drugs/DB09421ApprovedAlthough not currently available in any FDA-approved product, protirelin is a component of the TRH Test where it is used to test the response of the anterior pituitary gland in conditions such as secondary … It is a tri-peptide tropic hormone, released by the hypothalamus, that stimulates the release of Thyroid Stimulating Hormone (TSH) and prolactin from the anterior pituitary.
Categories: Tests for Thyreoidea FunctionProducts: Relefact Trh Inj 0.2mg/ml, TRH FERRING 0,2 MG/ML IV ENJEKSIYONLUK COZELTI ICEREN AMPUL, 1 ADETLurbinectedin
go.drugbank.com/drugs/DB12674ApprovedInvestigational[A214331] On June 15, 2020, the FDA granted accelerated approval and orphan drug designation to lurbinectedin for the treatment of adult patients with metastatic SCLC who have experienced disease progression … [L14336] This accelerated approval is based on the rate and duration of therapeutic response observed in ongoing clinical trials and is contingent on the verification of these results in confirmatory trials
Products: ZEPZELCA POWDER FOR SOLUTION FOR INFUSION 4MG/VIALInterferon alfa
go.drugbank.com/drugs/DB05258ApprovedInvestigationalWithdrawnNatural interferon alpha or Multiferon is obtained from the leukocyte fraction of human blood following induction with Sendai virus. … Interferon alpha proteins are mainly involved in innate immune response against viral infection.
Synonyms: IFN-αCategories: Interferon Type IBetamethasone
go.drugbank.com/drugs/DB00443ApprovedInvestigationalVet approved[A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. … Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties.
Mixtures: Diprogenta - Salbe, Diprosalic - SalbeCategories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use, Corticosteroids for Systemic UseAmivantamab
go.drugbank.com/drugs/DB16695ApprovedInvestigationalAmivantamab, also known as JNJ-61186372, is an anti-EGFR-MET bispecific antibody, derived from Chinese hamster ovary cells, approved for the treatment of adult patients with locally advanced or metastatic … [A235103,A235123] Patients with NSCLC with exon 20 insertion mutations in EGFR do not respond to tyrosine kinase inhibitors, and were generally treated with platinum-based therapy.
Products: RYBREVANT 350mg/7mL Concentrate for Solution for InfusionAnifrolumab
go.drugbank.com/drugs/DB11976ApprovedInvestigationalAnifrolumab, or MEDI-546, is a type 1 interferon receptor (IFNAR) inhibiting IgG1κ monoclonal antibody indicated in the treatment of adults with moderate to severe systemic lupus erythematosus. … [A237054] Anifrolumab has also been investigated for the treatment of Scleroderma.[A237044] Anifrolumab was granted FDA approval on 30 July 2021.[L34929]
Categories: Type I Interferon Receptor AntagonistProducts: SAPHNELO 300MG CONCENTRATE FOR SOLUTION FOR INFUSIONClofarabine
go.drugbank.com/drugs/DB00631ApprovedInvestigationalClofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at least two other types of treatment have failed. … Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand.
Products: EVOLTRA 1 MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION, NUCLOFAR Clofarabine 1mg/mL Concentrate for Solution for InfusionSulfur hexafluoride
go.drugbank.com/drugs/DB11104ApprovedInvestigationalSulfur hexafluoride is an ultrasound contrast agent indicated for use •in echocardiography to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border … in adult patients with suboptimal echocardiograms •in ultrasonography of the liver for characterization of focal liver lesions in adult and pediatric patients
Products: SONOVUE POWDER FOR DISPERSION FOR INJECTION 8 microlitres/ml