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Displaying results 821 - 830 of 9667 in total
  1. Drug

    Diflunisal

    go.drugbank.com/drugs/DB00861
    Approved

    Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the arachidonic acid pathway.

    Products: Dolobid Tab 250mg, Nu-diflunisal Tab 250mg
  2. Drug

    Sugammadex

    go.drugbank.com/drugs/DB06206
    ApprovedInvestigational

    Sugammadex (brand name Bridion) is marketed by Merck Sharp and Dohme, and was approved by the United States FDA on December 15, 2015.

    Products: BRIDION 100MG/ML SOLUTION FOR INJECTION, SUGAMMADEX EG
  3. Drug

    Anidulafungin

    go.drugbank.com/drugs/DB00362
    Approved

    There is preliminary evidence that it has a similar safety profile to caspofungin. … Anidulafungin or Eraxis is an anti-fungal drug manufactured by Pfizer that gained approval by the Food and Drug Administration (FDA) in February 21, 2006; it was previously known as LY303366.

    Products: ERAXIS 100MG FOR INJECTION, Eraxis 100mg For Injection
  4. Drug

    Acetylcysteine

    go.drugbank.com/drugs/DB06151
    ApprovedInvestigational

    [A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.[L31488] … [L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.

    Mixtures: ASCOVIT 1200/400MG SAŞE, 20 SAŞE, ASCOVIT 1200/400MG SAŞE, 30 SAŞEProducts: ACC SAFT 20MG/ML, HIDONAC SOLUTION FOR IV INFUSION (5G/25ML)
  5. Drug

    Dimethyl fumarate

    go.drugbank.com/drugs/DB08908
    ApprovedInvestigational

    [L43752] Dimethyl fumarate is marketed under the brand name Tecfidera, and it was the third oral disease-modifying agent for multiple sclerosis approved by the FDA, following [fingolimod] and [teriflunomide … It is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway that is activated

    Synonyms: (E)-But-2-enedioic acid dimethyl esterProducts: PMS-dimethyl Fumarate, DIMETILFUMARATO EG
  6. Drug

    Magnesium sulfate

    go.drugbank.com/drugs/DB00653
    ApprovedInvestigationalVet approved

    A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. … It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions.

    Mixtures: Magnesium Sulfate In 5% Dextrose Inj(20mg/ml), Calcium Lactate Et Magnesium SulfateProducts: Epsom Salt Pws 100%, TURKTIPSAN MAGNEZYUM SÜLFAT 40G/1000ML IV INFÜZYON IÇIN ÇÖZELTI , 1000 ML SETLI
  7. Drug

    Aminoglutethimide

    go.drugbank.com/drugs/DB00357
    ApprovedWithdrawn

    It was formerly used for its weak anticonvulsant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p454) … It also blocks the conversion of androgens to estrogens. Aminoglutethimide has been used in the treatment of advanced breast and prostate cancer.

    Products: Cytadren Tab 250mg
  8. Drug

    Olipudase alfa

    go.drugbank.com/drugs/DB12835
    ApprovedInvestigational

    [A251590] It was later approved by the European Commission on June 28, 2022 [L42740] and by the FDA on August 31, 2022.[L43145] … [A251590] It is the first and only enzyme replacement therapy in the world for the treatment of Acid Sphingomyelinase Deficiency (ASMD), also known as Niemann–Pick disease.

    Products: XENPOZYME 20MG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION
  9. Drug

    Mepolizumab

    go.drugbank.com/drugs/DB06612
    ApprovedInvestigational

    Mepolizumab was first approved by the FDA on November 4, 2015, as an add-on therapy for severe asthma and marketed under the brand name Nucala by GlaxoSmithKline. … This indication was subsequently expanded to cover EGPA on December 12, 2017, and HES on September 25, 2020.[L16518]

    Products: NUCALA® 100MG/ML SOLUCION INYECTABLE, NUCALA POWDER FOR SOLUTION FOR INJECTION 100mg
  10. Drug

    Desloratadine

    go.drugbank.com/drugs/DB00967
    ApprovedInvestigational

    Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system. … It is the active descarboethoxy metabolite of loratidine (a second generation histamine).

    Mixtures: Aerius D-12 Modified Release Tablets 2.5mg/120mg, AXIVOL PLUS 2.5 MG / 120MG EFERVESAN TABLET, 20 ADETProducts: CRISTHALER 50MG/100 ML, DESLORIX 50MG/100ML JARABE