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9-aminocamptothecin
go.drugbank.com/drugs/DB12515InvestigationalAminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates3,5-diiodothyropropionic acid
go.drugbank.com/drugs/DB12629InvestigationalDITPA has been investigated in Congestive Heart Failure.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesBalaglitazone
go.drugbank.com/drugs/DB12781InvestigationalBalaglitazone has been used in trials studying the treatment of Diabetes Mellitus, Type 2.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Inhibitorsp-Quaterphenyl
go.drugbank.com/drugs/DB12794Investigationalp-Quaterphenyl has been used in trials studying the treatment of Malaria.
Laniquidar
go.drugbank.com/drugs/DB12799InvestigationalLaniquidar has been used in trials studying the treatment of Breast Cancer.
Categories: P-glycoprotein inhibitorsTerpinen-4-ol
go.drugbank.com/drugs/DB12816InvestigationalTerpinen-4-ol is under investigation in clinical trial NCT01647217 (Demodex Blepharitis Treatment Study).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesTandospirone
go.drugbank.com/drugs/DB12833InvestigationalTandospirone has been used in trials studying the treatment of Schizophrenia.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesDihydralazine
go.drugbank.com/drugs/DB12945ApprovedWithdrawnDihydralazine is under investigation in clinical trial NCT00311974 (The Effect of Dihydralazine on Kidney Function and Hormones in Healthy Individuals).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsPexidartinib
go.drugbank.com/drugs/DB12978ApprovedInvestigationalPexidartinib is a selective tyrosine kinase inhibitor that works by inhibiting the colony-stimulating factor (CSF1)/CSF1 receptor pathway. Pexidartinib was originally developed by Daiichi Sankyo, Inc. and it was approved by the FDA in Au...
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesNepicastat
go.drugbank.com/drugs/DB12979InvestigationalNepicastat has been investigated for the treatment of Cocaine Dependence and Posttraumatic Stress Disorder.
Categories: P-glycoprotein substrates